Q86Y82: Syntaxin-12

General Information

Protein names	- Syntaxin-12
Gene names	STX12
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q86Y82

4 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSYGPLDMYR NPGPSGPQLR DFSSIIQTCS GNIQRISQAT AQIKNLMSQL GTKQDSSKLQ
        70         80         90        100        110        120
ENLQQLQHST NQLAKETNEL LKELGSLPLP LSTSEQRQQR LQKERLMNDF SAALNNFQAV
       130        140        150        160        170        180
QRRVSEKEKE SIARARAGSR LSAEERQREE QLVSFDSHEE WNQMQSQEDE VAITEQDLEL
       190        200        210        220        230        240
IKERETAIRQ LEADILDVNQ IFKDLAMMIH DQGDLIDSIE ANVESSEVHV ERATEQLQRA
       250        260        270
AYYQKKSRKK MCILVLVLSV IILILGLIIW LVYKTK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q86Y82-2-unknown	MSYGPL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q86Y82-2-Acetylation	SYGPLD...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q86Y82-2-Acetylation	SYGPLD...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q86Y82-2-Acetylation	SYGPLD...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q86Y82-218-unknown	SIEANV...	218			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q86Y82-218-	SIEANV...	218			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q86Y82-218-	SIEANV...	218			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q86Y82-218-	SIEANV...	218			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q86Y82-218-	SIEANV...	218			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q86Y82-218-	SIEANV...	218			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...IRQLEA	192	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000392577
	...VYKTK	276	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)