Q8BGD9: Eukaryotic translation initiation factor 4B

General Information

Protein names	- Eukaryotic translation initiation factor 4B - eIF-4B
Gene names	Eif4b
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8BGD9

13 N-termini

6 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAASAKKKNK KGKTISLTDF LAEDGGTGGG STYVPKPVSW ADETDDLEGD VSTTWHSNDD
        70         80         90        100        110        120
DVYRAPPIDR SILPTAPRAA REPNIDRSRL PKSPPYTAFL GNLPYDVTED SIKDFFRGLN
       130        140        150        160        170        180
ISAVRLPREP SNPDRLKGFG YAEFEDLDSL LSALSLNEES LGNRRIRVDV ADQAQDKDRD
       190        200        210        220        230        240
DRSFGRDRNR DSDKTDTDWR ARPTTDSFDD YPPRRGDDSF GDKYRDRYDS DRYRDGYRDG
       250        260        270        280        290        300
YRDGPRRDMD RYGGRDRYDD RGSRDYDRGY DSRIGSGRRA FGSGYRRDDD YRGGGDRYED
       310        320        330        340        350        360
RYDRRDDRSW SSRDDYSRDD YRRDDRGPPQ RPRLNLKPRS APKEDDASAS TSQSSRAASI
       370        380        390        400        410        420
FGGAKPVDTA AREREVEERL QKEQEKLQRQ LDEPKLDRRP RERHPSWRSE ETQERERSRT
       430        440        450        460        470        480
GSESSQTGAS ATSGRNTRRR ESEKSLENET LNKEEDCHSP TSKPPKPDQP LKVMPAPPPK
       490        500        510        520        530        540
ENAWVKRSSN PPARSQSSDT EQPSPTSGGG KVAAVQPPEE GPSRKDGNKV DVVGATQGQA
       550        560        570        580        590        600
GSCSRGPGDG GSRDHWKDLD RKDGKKDQDS RSAPEPKKPE ENPASKFSSA SKYAALSVDG
       610
EDEDEGDDCT E

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

13 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8BGD9-1-unknown	MAASAK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8BGD9-11-unknown	KGKTIS...	11	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q8BGD9-40-unknown	WADETD...	40	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34066
Q8BGD9-47-unknown	LEGDVS...	47		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q8BGD9-47-unmodified	LEGDVS...	47		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q8BGD9-148-unknown	DSLLSA...	148	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q8BGD9-154-unknown	LSLNEE...	154	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34067
Q8BGD9-359-unknown	SIFGGA...	359		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q8BGD9-360-unknown	IFGGAK...	360	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34068
Q8BGD9-361-unknown	FGGAKP...	361	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34069
Q8BGD9-363-unknown	GAKPVD...	363		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q8BGD9-363-unmodified	GAKPVD...	363		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q8BGD9-506-unknown	TSGGGK...	506	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34070

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PKPVSW	39	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34066
...SLLSAL	153	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34067
...SRAASI	359	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34068
...RAASIF	360	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34069
...EQPSPT	505	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34070
...DDCTE	611	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	39	PVSW.\|.WADE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	153	LSAL.\|.LSLN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	359	AASI.\|.IFGG	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	360	ASIF.\|.FGGA	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	505	PSPT.\|.TSGG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)