Q8CIN4: Serine/threonine-protein kinase PAK 2

General Information

Protein names	- Serine/threonine-protein kinase PAK 2 - 2.7.11.1 - Gamma-PAK - p21-activated kinase 2 - PAK-2 - PAK-2p27 - PAK-2p34
Gene names	Pak2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8CIN4

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSDNGELEDK PPAPPVRMSS TIFSTGGKDP LSANHSLKPL PSVPEEKKPR NKIISIFSGT
        70         80         90        100        110        120
EKGSKKKEKE RPEISPPSDF EHTIHVGFDA VTGEFTGMPE QWARLLQTSN ITKLEQKKNP
       130        140        150        160        170        180
QAVLDVLKFY DSNTVKQKYL SFTPPEKDGF PSGTPALNTK GSETSAVVTE EDDDDEDAAP
       190        200        210        220        230        240
PVIAPRPDHT KSIYTRSVID PIPAPVGDSN VDSGAKSSDK QKKKAKMTDE EIMEKLRTIV
       250        260        270        280        290        300
SIGDPKKKYT RYEKIGQGAS GTVFTATDVA LGQEVAIKQI NLQKQPKKEL IINEILVMKE
       310        320        330        340        350        360
LKNPNIVNFL DSYLVGDELF VVMEYLAGGS LTDVVTETCM DEAQIAAVCR ECLQALEFLH
       370        380        390        400        410        420
ANQVIHRDIK SDNVLLGMEG SVKLTDFGFC AQITPEQSKR STMVGTPYWM APEVVTRKAY
       430        440        450        460        470        480
GPKVDIWSLG IMAIEMVEGE PPYLNENPLR ALYLIATNGT PELQNPEKLS PIFRDFLNRC
       490        500        510        520
LEMDVEKRGS AKELLQHPFL KLAKPLSSLT PLILAAKEAM KSNR

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8CIN4-2-unknown	MSDNGE...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q8CIN4-2-unknown	MSDNGE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8CIN4-2-Acetylation	SDNGEL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8CIN4-2-Acetylation	SDNGEL...	2	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q8CIN4-2-Acetylation	SDNGEL...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q8CIN4-2-Acetylation	SDNGEL...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q8CIN4-213-unknown	SGAKSS...	213		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8CIN4-213-unknown	SGAKSS...	213		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q8CIN4-515-unknown	AAKEAM...	515		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29257

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DSNVDS	212	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TPLILA	514	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29257
...MKSNR	524	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	514	LILA.\|.AAKE	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PAK2_MOUSE @514

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)