Q91WQ3: Tyrosine--tRNA ligase, cytoplasmic

General Information

Protein names	- Tyrosine--tRNA ligase, cytoplasmic - 6.1.1.1 - Tyrosyl-tRNA synthetase - TyrRS - Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed
Gene names	Yars
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q91WQ3

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGDAPSPEEK LHLITRNLQE VLGEEKLKEI LKERELKVYW GTATTGKPHV AYFVPMSKIA
        70         80         90        100        110        120
DFLKAGCEVT ILFADLHAYL DNMKAPWELL ELRTSYYENV IKAMLESIGV PLEKLKFIKG
       130        140        150        160        170        180
TDYQLSKEYT LDVYRLSSVV TQHDAKKAGA EVVKQVEHPL LSGLLYPGLQ ALDEEYLKVD
       190        200        210        220        230        240
AQFGGVDQRK IFTFAEKYLP ALGYSKRVHL MNPMVPGLTG SKMSSSEEES KIDLLDRKED
       250        260        270        280        290        300
VKKKLKKAFC EPGNVENNGV LSFIKHVLFP LKSEFVILRD EKWGGNKTYT VYLELEKDFA
       310        320        330        340        350        360
AEVVHPGDLK NSVEVALNKL LDPIREKFNT PALKKLASAA YPDPSKQKPP AKGPAKNSEP
       370        380        390        400        410        420
EEVIPSRLDI RVGKILSVEK HPDADSLYVE KIDVGEAEPR TVVSGLVQFV PKEELQDRLV
       430        440        450        460        470        480
VVLCNLKPQK MRGVDSQGML LCASVEGVSR QVEPLDPPAG SAPGERVFVQ GYEKGQPDEE
       490        500        510        520
LKPKKKVFEK LQADFKISEE CIAQWKQTNF MTKLGFVSCK SLKGGNIS

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q91WQ3-1-Acetylation	MGDAPS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q91WQ3-2-Acetylation	GDAPSP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q91WQ3-2-Acetylation	GDAPSP...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q91WQ3-2-Acetylation	GDAPSP...	2	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q91WQ3-2-Acetylation	GDAPSP...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q91WQ3-2-Acetylation	GDAPSP...	2	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q91WQ3-7-unknown	PEEKLH...	7		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q91WQ3-223-unknown	MSSSEE...	223		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34139

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...LTGSKM	222	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34139
	...GGNIS	528	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	222	GSKM.\|.MSSS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)