Q92615: La-related protein 4B

General Information

Protein names	- La-related protein 4B - La ribonucleoprotein domain family member 4B - La ribonucleoprotein domain family member 5 - La-related protein 5
Gene names	LARP4B
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92615

6 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTSDQDAKVV AEPQTQRVQE GKDSAHLMNG PISQTTSQTS SIPPLSQVPA TKVSELNPNA
        70         80         90        100        110        120
EVWGAPVLHL EASSAADGVS AAWEEVAGHH ADRGPQGSDA NGDGDQGHEN AALPDPQESD
       130        140        150        160        170        180
PADMNALALG PSEYDSLPEN SETGGNESQP DSQEDPREVL KKTLEFCLSR ENLASDMYLI
       190        200        210        220        230        240
SQMDSDQYVP ITTVANLDHI KKLSTDVDLI VEVLRSLPLV QVDEKGEKVR PNQNRCIVIL
       250        260        270        280        290        300
REISESTPVE EVEALFKGDN LPKFINCEFA YNDNWFITFE TEADAQQAYK YLREEVKTFQ
       310        320        330        340        350        360
GKPIKARIKA KAIAINTFLP KNGFRPLDVS LYAQQRYATS FYFPPMYSPQ QQFPLYSLIT
       370        380        390        400        410        420
PQTWSATHSY LDPPLVTPFP NTGFINGFTS PAFKPAASPL TSLRQYPPRS RNPSKSHLRH
       430        440        450        460        470        480
AIPSAERGPG LLESPSIFNF TADRLINGVR SPQTRQAGQT RTRIQNPSAY AKREAGPGRV
       490        500        510        520        530        540
EPGSLESSPG LGRGRKNSFG YRKKREEKFT SSQTQSPTPP KPPSPSFELG LSSFPPLPGA
       550        560        570        580        590        600
AGNLKTEDLF ENRLSSLIIG PSKERTLSAD ASVNTLPVVV SREPSVPASC AVSATYERSP
       610        620        630        640        650        660
SPAHLPDDPK VAEKQRETHS VDRLPSALTA TACKSVQVNG AATELRKPSY AEICQRTSKE
       670        680        690        700        710        720
PPSSPLQPQK EQKPNTVGCG KEEKKLAEPA ERYREPPALK STPGAPRDQR RPAGGRPSPS
       730
AMGKRLSREQ STPPKSPQ

Isoforms

Sequence View

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Evidence Codes:

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Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92615-1-Acetylation	MTSDQD...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92615-1-Acetylation	MTSDQD...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q92615-1-Acetylation	MTSDQD...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q92615-2-unknown	TSDQDA...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q92615-2-unknown	TSDQDA...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q92615-41-	SIPPLS...	41			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q92615-41-	SIPPLS...	41			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q92615-78-	GVSAAW...	78			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q92615-136-	SLPENS...	136			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q92615-715-unknown	GRPSPS...	715		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6628

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...VSELNP	57	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000390556
...LALGPS	131	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000385229
...RRPAGG	714	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6628
...PKSPQ	738	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...PKSPQ	738		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...PKSPQ	738		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...PKSPQ	738		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...PKSPQ	738		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	714	PAGG.\|.GRPS	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)