Q96AG4: Leucine-rich repeat-containing protein 59

General Information

Protein names	- Leucine-rich repeat-containing protein 59 - Ribosome-binding protein p34 - p34 - Leucine-rich repeat-containing protein 59, N-terminally processed
Gene names	LRRC59
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96AG4

4 N-termini

3 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MTKAGSKGGN LRDKLDGNEL DLSLSDLNEV PVKELAALPK ATILDLSCNK LTTLPSDFCG
        70         80         90        100        110        120
LTHLVKLDLS KNKLQQLPAD FGRLVNLQHL DLLNNKLVTL PVSFAQLKNL KWLDLKDNPL
       130        140        150        160        170        180
DPVLAKVAGD CLDEKQCKQC ANKVLQHMKA VQADQERERQ RRLEVEREAE KKREAKQRAK
       190        200        210        220        230        240
EAQERELRKR EKAEEKERRR KEYDALKAAK REQEKKPKKE ANQAPKSKSG SRPRKPPPRK
       250        260        270        280        290        300
HTRSWAVLKL LLLLLLFGVA GGLVACRVTE LQQQPLCTSV NTIYDNAVQG LRRHEILQWV

LQTDSQQ

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96AG4-1-Acetylation	MTKAGS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96AG4-1-Acetylation	MTKAGS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q96AG4-1-Acetylation	MTKAGS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q96AG4-2-acetylation	TKAGSK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q96AG4-2-acetylation	TKAGSK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q96AG4-2-acetylation	TKAGSK...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96AG4-57-unknown	DFCGLT...	57		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19734
Q96AG4-89-unknown	HLDLLN...	89		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6656

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TTLPSD	56	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19734
...LVNLQH	88	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6656
...TDSQQ	307	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	56	LPSD.\|.DFCG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CATL1_HUMAN	88	NLQH.\|.HLDL	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)