Q96EN9: Required for excision 1-B domain-containing protein {ECO:0000305}

General Information

Protein names	- Required for excision 1-B domain-containing protein {ECO:0000305}
Gene names	C19orf60
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96EN9

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Uncharacterized protein C19orf60 - Isoform 3 of Uncharacterized protein C19orf60 - Isoform 2 of Required for excision 1-B domain-containing protein - Isoform 3 of Required for excision 1-B domain-containing protein

Sequence View

        10         20         30         40         50         60
MITETAAEPT VPAVPAAEEA TEARGREEPA WPWKDAPIRT LVQRIHQLQA ERAQGFRRLE
        70         80         90        100        110        120
EWLAPVQGLR AWGRGLRVPT CRRGHRQYLR SGPDYDFARY RSTVHGVTQA FAAASREVLA
       130        140        150        160        170        180
VEAELGGPRR QPLLAGHVRS LQELEQTRLG TVALLQLMET PELAGQEDAV RMQQLKMKVI
       190        200
KTMEAISEVL QDLRFDAESA E         10         20         30         40         50         60
MITETAAEPT VPAVPAAEEA TEARGREEPA WPWKDAPIRT LVQRIHQLQA ERAQGFRRLE
        70         80         90        100        110        120
EWLAPVQGLR AWGRGLRVPT CRRGHRQYLR SGPDYDFARY RSTVHGVTQA FAAASREVLA
       130        140        150        160        170        180
VEAELGGPRR QPLLAGHVRS LQELEQTRLG TVALLQLMET PELAGQEDAV RMQQLKMKVI
       190        200
KTMEAISEVL QDLRFDAESA E         10         20         30         40         50         60
MITETAAEPT VPAVPAAEEA TEARGREEPA WPWKDAPIRT LVQRIHQLQA ERAQGFRRLE
        70         80         90        100        110        120
EWLAPVQGLR AWGRGLRVPT CRRGHRQYLR SGPDYDFARY RSTVHGVTQA FAAASREVLA
       130        140        150        160        170        180
VEAELGGPRR QPLLAGHVRS LQELEQTRLG TVALLQLMET PELAGQEDAV RMQQLKMKVI
       190        200
KTMEAISEVL QDLRFDAESA E         10         20         30         40         50         60
MITETAAEPT VPAVPAAEEA TEARGREEPA WPWKDAPIRT LVQRIHQLQA ERAQGFRRLE
        70         80         90        100        110        120
EWLAPVQGLR AWGRGLRVPT CRRGHRQYLR SGPDYDFARY RSTVHGVTQA FAAASREVLA
       130        140        150        160        170        180
VEAELGGPRR QPLLAGHVRS LQELEQTRLG TVALLQLMET PELAGQEDAV RMQQLKMKVI
       190        200
KTMEAISEVL QDLRFDAESA E

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96EN9-1-acetylation	MITETA...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q96EN9-1-acetylation	MITETA...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt163090
Q96EN9-1-unknown	MITETA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96EN9-1-unknown	MITETA...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71829
Q96EN9-1-	MITETA...	1			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q96EN9-1-	MITETA...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q96EN9-1-	MITETA...	1			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q96EN9-1-	MITETA...	1			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QLKMKV	178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67446
...QLKMKV	178	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91889
...AESAE	201	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...AESAE	201	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67447

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)