Q99807: 5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03194}

General Information

Protein names	- 5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03194} - DMQ hydroxylase {ECO:0000255\|HAMAP-Rule:MF_03194} - 1.14.13.- {ECO:0000255\|HAMAP-Rule:MF_03194} - Timing protein clk-1 homolog {ECO:0000255\|HAMAP-Rule:MF_03194} - Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000255\|HAMAP-Rule:MF_03194}
Gene names	COQ7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99807

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Ubiquinone biosynthesis protein COQ7 homolog - Isoform 2 of 5-demethoxyubiquinone hydroxylase, mitochondrial

Sequence View

        10         20         30         40         50         60
MSCAGAAAAP RLWRLRPGAR RSLSAYGRRT SVRFRSSGMT LDNISRAAVD RIIRVDHAGE
        70         80         90        100        110        120
YGANRIYAGQ MAVLGRTSVG PVIQKMWDQE KDHLKKFNEL MVTFRVRPTV LMPLWNVLGF
       130        140        150        160        170        180
ALGAGTALLG KEGAMACTVA VEESIAHHYN NQIRTLMEED PEKYEELLQL IKKFRDEELE
       190        200        210
HHDIGLDHDA ELAPAYAVLK SIIQAGCRVA IYLSERL         10         20         30         40         50         60
MSCAGAAAAP RLWRLRPGAR RSLSAYGRRT SVRFRSSGMT LDNISRAAVD RIIRVDHAGE
        70         80         90        100        110        120
YGANRIYAGQ MAVLGRTSVG PVIQKMWDQE KDHLKKFNEL MVTFRVRPTV LMPLWNVLGF
       130        140        150        160        170        180
ALGAGTALLG KEGAMACTVA VEESIAHHYN NQIRTLMEED PEKYEELLQL IKKFRDEELE
       190        200        210
HHDIGLDHDA ELAPAYAVLK SIIQAGCRVA IYLSERL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99807-36-unknown	SSGMTL...	36		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q99807-36-unknown	SSGMTL...	36	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99807-36-	SSGMTL...	36		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q99807-36-	SSGMTL...	36		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q99807-36-	SSGMTL...	36		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q99807-36-	SSGMTL...	36		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q99807-36-	SSGMTL...	36		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q99807-37-unknown	SGMTLD...	37	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99807-39-unknown	MTLDNI...	39	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71435

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...LSERL	217	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...LSERL	217	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt67053

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)