Q99JY9: Actin-related protein 3

General Information

Protein names	- Actin-related protein 3 - Actin-like protein 3
Gene names	Actr3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99JY9

10 N-termini

8 C-termini

12 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGRLPACVV DCGTGYTKLG YAGNTEPQFI IPSCIAIKES AKVGDQAQRR VMKGVDDLDF
        70         80         90        100        110        120
FIGDEAIEKP TYATKWPIRH GIVEDWDLME RFMEQVIFKY LRAEPEDHYF LLTEPPLNTP
       130        140        150        160        170        180
ENREYTAEIM FESFNVPGLY IAVQAVLALA ASWTSRQVGE RTLTGTVIDS GDGVTHVIPV
       190        200        210        220        230        240
AEGYVIGSCI KHIPIAGRDI TYFIQQLLRD REVGIPPEQS LETAKAVKER YSYVCPDLVK
       250        260        270        280        290        300
EFNKYDTDGS KWIKQYTGVN AISKKEFSID VGYERFLGPE IFFHPEFANP DFTQPISEVV
       310        320        330        340        350        360
DEVIQNCPID VRRPLYKNIV LSGGSTMFRD FGRRLQRDLK RTVDARLKLS EELSGGRLKP
       370        380        390        400        410
KPIDVQVITH HMQRYAVWFG GSMLASTPEF YQVCHTKKDY EEIGPSICRH NPVFGVMS

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

10 N-termini - 8 C-termini - 12 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99JY9-2-unknown	MAGRLP...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q99JY9-2-unknown	MAGRLP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99JY9-2-Acetylation	AGRLPA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99JY9-2-Acetylation	AGRLPA...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q99JY9-35-unknown	IAIKES...	35		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29298
Q99JY9-35-unknown	IAIKES...	35		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34165
Q99JY9-35-unknown	IAIKES...	35		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30952
Q99JY9-37-unknown	IKESAK...	37		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29299
Q99JY9-37-unknown	IKESAK...	37		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30953
Q99JY9-64-unmodified	DEAIEK...	64			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q99JY9-222-unknown	ETAKAV...	222		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29300
Q99JY9-222-unknown	ETAKAV...	222		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30954
Q99JY9-299-unknown	VVDEVI...	299		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30955
Q99JY9-302-unknown	EVIQNC...	302		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29301
Q99JY9-319-unknown	IVLSGG...	319		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30956
Q99JY9-391-unknown	YQVCHT...	391		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29302
Q99JY9-391-unknown	YQVCHT...	391		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30957

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IIPSCI	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29298
...IIPSCI	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34165
...IIPSCI	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30952
...PSCIAI	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29299
...PSCIAI	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30953
...PEQSLE	221	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29300
...PEQSLE	221	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30954
...QPISEV	298	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30955
...SEVVDE	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29301
...PLYKNI	318	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30956
...STPEFY	390	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29302
...STPEFY	390	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30957
...FGVMS	418	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	34	PSCI.\|.IAIK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ARP3_MOUSE @34
MMP2_MOUSE	34	PSCI.\|.IAIK	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	34	PSCI.\|.IAIK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ARP3_MOUSE @34
CATD_MOUSE	36	CIAI.\|.IKES	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ARP3_MOUSE @36
CATE_MOUSE	36	CIAI.\|.IKES	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ARP3_MOUSE @36
CATD_MOUSE	221	QSLE.\|.ETAK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ARP3_MOUSE @221
CATE_MOUSE	221	QSLE.\|.ETAK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ARP3_MOUSE @221
CATE_MOUSE	298	ISEV.\|.VVDE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ARP3_MOUSE @298
CATD_MOUSE	301	VVDE.\|.EVIQ	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ARP3_MOUSE @301
CATE_MOUSE	318	YKNI.\|.IVLS	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ARP3_MOUSE @318
CATD_MOUSE	390	PEFY.\|.YQVC	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ARP3_MOUSE @390
CATE_MOUSE	390	PEFY.\|.YQVC	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ARP3_MOUSE @390

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)