Q99KH8: Serine/threonine-protein kinase 24

General Information

Protein names	- Serine/threonine-protein kinase 24 - 2.7.11.1 - Mammalian STE20-like protein kinase 3 - MST-3 - STE20-like kinase MST3 - Serine/threonine-protein kinase 24 35 kDa subunit - Mammalian STE20-like protein kinase 3 N-terminal - MST3/N - Serine/threonine-protein kinase 24 12 kDa subunit - Mammalian STE20-like protein kinase 3 C-terminal - MST3/C
Gene names	Stk24
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99KH8

7 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAHSPVQSGL PGMQNLKADP EELFTKLEKI GKGSFGEVFK GIDNRTQKVV AIKIIDLEEA
        70         80         90        100        110        120
EDEIEDIQQE ITVLSQCDSP YVTKYYGSYL KDTKLWIIME YLGGGSALDL LEPGPLDEIQ
       130        140        150        160        170        180
IATILREILK GLDYLHSEKK IHRDIKAANV LLSEHGEVKL ADFGVAGQLT DTQIKRNTFV
       190        200        210        220        230        240
GTPFWMAPEV IKQSAYDSKA DIWSLGITAI ELAKGEPPHS ELHPMKVLFL IPKNNPPTLE
       250        260        270        280        290        300
GNYSKPLKEF VEACLNKEPS FRPTAKELLK HKFIIRNAKK TSYLTELIDR YKRWKAEQSH
       310        320        330        340        350        360
EDSSSEDSDV ETDGQASGGS DSGDWIFTIR EKDPKNLENG TLQLSDLERN KMKDIPKRPF
       370        380        390        400        410        420
SQCLSTIISP LFAELKEKSQ ACGGNLGSIE ELRGAIYLAE EACPGISDTM VAQLVQRLQR
       430
YSLSGGGASA H

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99KH8-2-unknown	MAHSPV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99KH8-2-Acetylation	AHSPVQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99KH8-103-unknown	GGGSAL...	103		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q99KH8-103-unknown	GGGSAL...	103		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99KH8-103-unknown	GGGSAL...	103		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q99KH8-161-unknown	ADFGVA...	161		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30960
Q99KH8-314-unknown	GQASGG...	314		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99KH8-314-unknown	GQASGG...	314			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
Q99KH8-314-unknown	GQASGG...	314		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q99KH8-314-unmodified	GQASGG...	314			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q99KH8-373-unknown	AELKEK...	373		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29305

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GEVKLA	160	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30960
...DVETDG	313	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ISPLFA	372	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29305
...GASAH	431	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	160	VKLA.\|.ADFG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> STK24_MOUSE @160
CATD_MOUSE	372	PLFA.\|.AELK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> STK24_MOUSE @372

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)