Q99LS3: Phosphoserine phosphatase

General Information

Protein names	- Phosphoserine phosphatase - PSP - PSPase - 3.1.3.3 - O-phosphoserine phosphohydrolase
Gene names	Psph
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99LS3

3 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVSHSELRKL FCSADAVCFD VDSTVIREEG IDELAKFCGV EAAVSEMTRR AMGGALPFKD
        70         80         90        100        110        120
ALTQRLALIQ PSRDQVQRLL AEHPPHLTPG IRELVSRLQE RNVQVFLISG GFRSIVEHVA
       130        140        150        160        170        180
AKLNIPTTNV FANRLKFYFN GEYAGFDEMQ PTAESGGKGK VIRFLKEKFH FKKIIMIGDG
       190        200        210        220
ATDMEACPPA DAFIGFGGNV IRQQVKDNAK WYITDFVELL GELEE

Isoforms

Sequence View

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Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q99LS3-1-Acetylation	MVSHSE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99LS3-79-unknown	LLAEHP...	79		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34174
Q99LS3-194-unknown	IGFGGN...	194		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29313

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LPFKDA	60	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000116292
...DQVQRL	78	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34174
...PADAFI	193	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29313
...GELEE	225	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	78	VQRL.\|.LLAE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	193	DAFI.\|.IGFG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> SERB_MOUSE @193

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)