Q99LX0: Protein/nucleic acid deglycase DJ-1 {ECO:0000250|UniProtKB:Q99497}

General Information

Protein names	- Protein/nucleic acid deglycase DJ-1 {ECO:0000250\|UniProtKB:Q99497} - 3.1.2.- {ECO:0000250\|UniProtKB:Q99497} - 3.5.1.- {ECO:0000250\|UniProtKB:Q99497} - 3.5.1.124 {ECO:0000250\|UniProtKB:Q99497} - Maillard deglycase {ECO:0000250\|UniProtKB:Q99497} - Parkinson disease protein 7 homolog {ECO:0000305} - Parkinsonism-associated deglycase {ECO:0000250\|UniProtKB:Q99497} - Protein DJ-1 {ECO:0000305} - DJ-1
Gene names	Park7
Organism	Mus musculus
Protease Family
Protease ID	C56.002
Chromosome location
UniProt ID	Q99LX0

3 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASKRALVIL AKGAEEMETV IPVDVMRRAG IKVTVAGLAG KDPVQCSRDV MICPDTSLED
        70         80         90        100        110        120
AKTQGPYDVV VLPGGNLGAQ NLSESPMVKE ILKEQESRKG LIAAICAGPT ALLAHEVGFG
       130        140        150        160        170        180
CKVTTHPLAK DKMMNGSHYS YSESRVEKDG LILTSRGPGT SFEFALAIVE ALVGKDMANQ

VKAPLVLKD

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q99LX0-1-unknown	MASKRA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q99LX0-83-unknown	SESPMV...	83	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30985
Q99LX0-83-unknown	SESPMV...	83	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29314
Q99LX0-180-unknown	QVKAPL...	180	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34175

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...	0	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GAQNLS	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30985
...GAQNLS	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29314
...QNLSES	84	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120832
...DKMMNG	135	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115875
...KDMANQ	179	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34175

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	82	QNLS.\|.SESP	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> PARK7_MOUSE @82
CATD_MOUSE	82	QNLS.\|.SESP	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> PARK7_MOUSE @82
MMP2_MOUSE	179	MANQ.\|.QVKA	inferred from experiment	unknown	MEROPS	Merops MMP2_MOUSE -> PARK7_MOUSE @179

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)