Q99PT1: Rho GDP-dissociation inhibitor 1

General Information

Protein names	- Rho GDP-dissociation inhibitor 1 - Rho GDI 1 - GDI-1 - Rho-GDI alpha
Gene names	Arhgdia
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99PT1

14 N-termini

9 C-termini

9 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAEQEPTAEQ LAQIAAENEE DEHSVNYKPP AQKSIQEIQE LDKDDESLRK YKEALLGRVA
        70         80         90        100        110        120
VSADPNVPNV IVTRLTLVCS TAPGPLELDL TGDLESFKKQ SFVLKEGVEY RIKISFRVNR
       130        140        150        160        170        180
EIVSGMKYIQ HTYRKGVKID KTDYMVGSYG PRAEEYEFLT PMEEAPKGML ARGSYNIKSR
       190        200
FTDDDKTDHL SWEWNLTIKK EWKD

Isoforms

Sequence View

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Methodology:

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Protein Neighborhood

Domains & Features

14 N-termini - 9 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99PT1-2-unknown	MAEQEP...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q99PT1-2-unknown	MAEQEP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99PT1-2-Acetylation	AEQEPT...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99PT1-2-Acetylation	AEQEPT...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q99PT1-6-unknown	PTAEQL...	6		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q99PT1-14-unknown	IAAENE...	14		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34180
Q99PT1-30-unknown	PAQKSI...	30		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q99PT1-32-unknown	QKSIQE...	32		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34181
Q99PT1-35-unknown	IQEIQE...	35		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34182
Q99PT1-37-unmodified	EIQELD...	37			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q99PT1-38-unknown	IQELDK...	38		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30990
Q99PT1-38-unknown	IQELDK...	38		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34183
Q99PT1-59-unmodified	VAVSAD...	59			N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q99PT1-99-unknown	KQSFVL...	99		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34184
Q99PT1-126-unknown	MKYIQH...	126		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34185
Q99PT1-144-unknown	YMVGSY...	144		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34186
Q99PT1-145-unknown	MVGSYG...	145		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34187

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EQLAQI	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34180
...YKPPAQ	31	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34181
...PAQKSI	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34182
...KSIQEI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30990
...KSIQEI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34183
...LESFKK	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34184
...EIVSGM	125	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34185
...IDKTDY	143	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34186
...DKTDYM	144	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34187
...KEWKD	204	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	13	LAQI.\|.IAAE	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> GDIR1_MOUSE @13
MMP2_MOUSE	31	PPAQ.\|.QKSI	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> GDIR1_MOUSE @31
MMP2_MOUSE	34	QKSI.\|.IQEI	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	37	IQEI.\|.IQEL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> GDIR1_MOUSE @37
MMP2_MOUSE	37	IQEI.\|.IQEL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	98	SFKK.\|.KQSF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	125	VSGM.\|.MKYI	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	143	KTDY.\|.YMVG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	144	TDYM.\|.MVGS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)