Q9BS40: Latexin

General Information

Protein names	- Latexin - Endogenous carboxypeptidase inhibitor - ECI - Protein MUM - Tissue carboxypeptidase inhibitor - TCI
Gene names	LXN
Organism	Homo sapiens
Protease Family
Protease ID	I47.001
Chromosome location
UniProt ID	Q9BS40

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEIPPTNYPA SRAALVAQNY INYQQGTPHR VFEVQKVKQA SMEDIPGRGH KYHLKFAVEE
        70         80         90        100        110        120
IIQKQVKVNC TAEVLYPSTG QETAPEVNFT FEGETGKNPD EEDNTFYQRL KSMKEPLEAQ
       130        140        150        160        170        180
NIPDNFGNVS PEMTLVLHLA WVACGYIIWQ NSTEDTWYKM VKIQTVKQVQ RNDDFIELDY
       190        200        210        220
TILLHNIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEVQ LE

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BS40-1-unknown	MEIPPT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BS40-1-acetylation	MEIPPT...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9BS40-1-acetylation	MEIPPT...	1	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9BS40-13-acetylation	AALVAQ...	13	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
Q9BS40-20-unknown	YINYQQ...	20		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19974

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...LVAQNY	19	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19974
	...EVQLE	222	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP11_HUMAN	19	AQNY.\|.YINY	inferred from experiment	unknown	MEROPS		Merops MMP11_HUMAN -> LXN_HUMAN @19

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)