Q9BXS9: Solute carrier family 26 member 6

General Information

Protein names	- Solute carrier family 26 member 6 - Anion exchange transporter - Pendrin-like protein 1 - Pendrin-L1
Gene names	SLC26A6
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9BXS9

5 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Solute carrier family 26 member 6 - Isoform 3 of Solute carrier family 26 member 6 - Isoform 4 of Solute carrier family 26 member 6 - Isoform 5 of Solute carrier family 26 member 6 - Isoform 6 of Solute carrier family 26 member 6 - Isoform 7 of Solute carrier family 26 member 6

Sequence View

        10         20         30         40         50         60
MGLADASGPR DTQALLSATQ AMDLRRRDYH MERPLLNQEH LEELGRWGSA PRTHQWRTWL
        70         80         90        100        110        120
QCSRARAYAL LLQHLPVLVW LPRYPVRDWL LGDLLSGLSV AIMQLPQGLA YALLAGLPPV
       130        140        150        160        170        180
FGLYSSFYPV FIYFLFGTSR HISVGTFAVM SVMVGSVTES LAPQALNDSM INETARDAAR
       190        200        210        220        230        240
VQVASTLSVL VGLFQVGLGL IHFGFVVTYL SEPLVRGYTT AAAVQVFVSQ LKYVFGLHLS
       250        260        270        280        290        300
SHSGPLSLIY TVLEVCWKLP QSKVGTVVTA AVAGVVLVVV KLLNDKLQQQ LPMPIPGELL
       310        320        330        340        350        360
TLIGATGISY GMGLKHRFEV DVVGNIPAGL VPPVAPNTQL FSKLVGSAFT IAVVGFAIAI
       370        380        390        400        410        420
SLGKIFALRH GYRVDSNQEL VALGLSNLIG GIFQCFPVSC SMSRSLVQES TGGNSQVAGA
       430        440        450        460        470        480
ISSLFILLII VKLGELFHDL PKAVLAAIII VNLKGMLRQL SDMRSLWKAN RADLLIWLVT
       490        500        510        520        530        540
FTATILLNLD LGLVVAVIFS LLLVVVRTQM PHYSVLGQVP DTDIYRDVAE YSEAKEVRGV
       550        560        570        580        590        600
KVFRSSATVY FANAEFYSDA LKQRCGVDVD FLISQKKKLL KKQEQLKLKQ LQKEEKLRKQ
       610        620        630        640        650        660
AASPKGASVS INVNTSLEDM RSNNVEDCKM MQVSSGDKME DATANGQEDS KAPDGSTLKA
       670        680        690        700        710        720
LGLPQPDFHS LILDLGALSF VDTVCLKSLK NIFHDFREIE VEVYMAACHS PVVSQLEAGH
       730        740        750
FFDASITKKH LFASVHDAVT FALQHPRPVP DSPVSVTRL         10         20         30         40         50         60
MGLADASGPR DTQALLSATQ AMDLRRRDYH MERPLLNQEH LEELGRWGSA PRTHQWRTWL
        70         80         90        100        110        120
QCSRARAYAL LLQHLPVLVW LPRYPVRDWL LGDLLSGLSV AIMQLPQGLA YALLAGLPPV
       130        140        150        160        170        180
FGLYSSFYPV FIYFLFGTSR HISVGTFAVM SVMVGSVTES LAPQALNDSM INETARDAAR
       190        200        210        220        230        240
VQVASTLSVL VGLFQVGLGL IHFGFVVTYL SEPLVRGYTT AAAVQVFVSQ LKYVFGLHLS
       250        260        270        280        290        300
SHSGPLSLIY TVLEVCWKLP QSKVGTVVTA AVAGVVLVVV KLLNDKLQQQ LPMPIPGELL
       310        320        330        340        350        360
TLIGATGISY GMGLKHRFEV DVVGNIPAGL VPPVAPNTQL FSKLVGSAFT IAVVGFAIAI
       370        380        390        400        410        420
SLGKIFALRH GYRVDSNQEL VALGLSNLIG GIFQCFPVSC SMSRSLVQES TGGNSQVAGA
       430        440        450        460        470        480
ISSLFILLII VKLGELFHDL PKAVLAAIII VNLKGMLRQL SDMRSLWKAN RADLLIWLVT
       490        500        510        520        530        540
FTATILLNLD LGLVVAVIFS LLLVVVRTQM PHYSVLGQVP DTDIYRDVAE YSEAKEVRGV
       550        560        570        580        590        600
KVFRSSATVY FANAEFYSDA LKQRCGVDVD FLISQKKKLL KKQEQLKLKQ LQKEEKLRKQ
       610        620        630        640        650        660
AASPKGASVS INVNTSLEDM RSNNVEDCKM MQVSSGDKME DATANGQEDS KAPDGSTLKA
       670        680        690        700        710        720
LGLPQPDFHS LILDLGALSF VDTVCLKSLK NIFHDFREIE VEVYMAACHS PVVSQLEAGH
       730        740        750
FFDASITKKH LFASVHDAVT FALQHPRPVP DSPVSVTRL         10         20         30         40         50         60
MGLADASGPR DTQALLSATQ AMDLRRRDYH MERPLLNQEH LEELGRWGSA PRTHQWRTWL
        70         80         90        100        110        120
QCSRARAYAL LLQHLPVLVW LPRYPVRDWL LGDLLSGLSV AIMQLPQGLA YALLAGLPPV
       130        140        150        160        170        180
FGLYSSFYPV FIYFLFGTSR HISVGTFAVM SVMVGSVTES LAPQALNDSM INETARDAAR
       190        200        210        220        230        240
VQVASTLSVL VGLFQVGLGL IHFGFVVTYL SEPLVRGYTT AAAVQVFVSQ LKYVFGLHLS
       250        260        270        280        290        300
SHSGPLSLIY TVLEVCWKLP QSKVGTVVTA AVAGVVLVVV KLLNDKLQQQ LPMPIPGELL
       310        320        330        340        350        360
TLIGATGISY GMGLKHRFEV DVVGNIPAGL VPPVAPNTQL FSKLVGSAFT IAVVGFAIAI
       370        380        390        400        410        420
SLGKIFALRH GYRVDSNQEL VALGLSNLIG GIFQCFPVSC SMSRSLVQES TGGNSQVAGA
       430        440        450        460        470        480
ISSLFILLII VKLGELFHDL PKAVLAAIII VNLKGMLRQL SDMRSLWKAN RADLLIWLVT
       490        500        510        520        530        540
FTATILLNLD LGLVVAVIFS LLLVVVRTQM PHYSVLGQVP DTDIYRDVAE YSEAKEVRGV
       550        560        570        580        590        600
KVFRSSATVY FANAEFYSDA LKQRCGVDVD FLISQKKKLL KKQEQLKLKQ LQKEEKLRKQ
       610        620        630        640        650        660
AASPKGASVS INVNTSLEDM RSNNVEDCKM MQVSSGDKME DATANGQEDS KAPDGSTLKA
       670        680        690        700        710        720
LGLPQPDFHS LILDLGALSF VDTVCLKSLK NIFHDFREIE VEVYMAACHS PVVSQLEAGH
       730        740        750
FFDASITKKH LFASVHDAVT FALQHPRPVP DSPVSVTRL         10         20         30         40         50         60
MGLADASGPR DTQALLSATQ AMDLRRRDYH MERPLLNQEH LEELGRWGSA PRTHQWRTWL
        70         80         90        100        110        120
QCSRARAYAL LLQHLPVLVW LPRYPVRDWL LGDLLSGLSV AIMQLPQGLA YALLAGLPPV
       130        140        150        160        170        180
FGLYSSFYPV FIYFLFGTSR HISVGTFAVM SVMVGSVTES LAPQALNDSM INETARDAAR
       190        200        210        220        230        240
VQVASTLSVL VGLFQVGLGL IHFGFVVTYL SEPLVRGYTT AAAVQVFVSQ LKYVFGLHLS
       250        260        270        280        290        300
SHSGPLSLIY TVLEVCWKLP QSKVGTVVTA AVAGVVLVVV KLLNDKLQQQ LPMPIPGELL
       310        320        330        340        350        360
TLIGATGISY GMGLKHRFEV DVVGNIPAGL VPPVAPNTQL FSKLVGSAFT IAVVGFAIAI
       370        380        390        400        410        420
SLGKIFALRH GYRVDSNQEL VALGLSNLIG GIFQCFPVSC SMSRSLVQES TGGNSQVAGA
       430        440        450        460        470        480
ISSLFILLII VKLGELFHDL PKAVLAAIII VNLKGMLRQL SDMRSLWKAN RADLLIWLVT
       490        500        510        520        530        540
FTATILLNLD LGLVVAVIFS LLLVVVRTQM PHYSVLGQVP DTDIYRDVAE YSEAKEVRGV
       550        560        570        580        590        600
KVFRSSATVY FANAEFYSDA LKQRCGVDVD FLISQKKKLL KKQEQLKLKQ LQKEEKLRKQ
       610        620        630        640        650        660
AASPKGASVS INVNTSLEDM RSNNVEDCKM MQVSSGDKME DATANGQEDS KAPDGSTLKA
       670        680        690        700        710        720
LGLPQPDFHS LILDLGALSF VDTVCLKSLK NIFHDFREIE VEVYMAACHS PVVSQLEAGH
       730        740        750
FFDASITKKH LFASVHDAVT FALQHPRPVP DSPVSVTRL         10         20         30         40         50         60
MGLADASGPR DTQALLSATQ AMDLRRRDYH MERPLLNQEH LEELGRWGSA PRTHQWRTWL
        70         80         90        100        110        120
QCSRARAYAL LLQHLPVLVW LPRYPVRDWL LGDLLSGLSV AIMQLPQGLA YALLAGLPPV
       130        140        150        160        170        180
FGLYSSFYPV FIYFLFGTSR HISVGTFAVM SVMVGSVTES LAPQALNDSM INETARDAAR
       190        200        210        220        230        240
VQVASTLSVL VGLFQVGLGL IHFGFVVTYL SEPLVRGYTT AAAVQVFVSQ LKYVFGLHLS
       250        260        270        280        290        300
SHSGPLSLIY TVLEVCWKLP QSKVGTVVTA AVAGVVLVVV KLLNDKLQQQ LPMPIPGELL
       310        320        330        340        350        360
TLIGATGISY GMGLKHRFEV DVVGNIPAGL VPPVAPNTQL FSKLVGSAFT IAVVGFAIAI
       370        380        390        400        410        420
SLGKIFALRH GYRVDSNQEL VALGLSNLIG GIFQCFPVSC SMSRSLVQES TGGNSQVAGA
       430        440        450        460        470        480
ISSLFILLII VKLGELFHDL PKAVLAAIII VNLKGMLRQL SDMRSLWKAN RADLLIWLVT
       490        500        510        520        530        540
FTATILLNLD LGLVVAVIFS LLLVVVRTQM PHYSVLGQVP DTDIYRDVAE YSEAKEVRGV
       550        560        570        580        590        600
KVFRSSATVY FANAEFYSDA LKQRCGVDVD FLISQKKKLL KKQEQLKLKQ LQKEEKLRKQ
       610        620        630        640        650        660
AASPKGASVS INVNTSLEDM RSNNVEDCKM MQVSSGDKME DATANGQEDS KAPDGSTLKA
       670        680        690        700        710        720
LGLPQPDFHS LILDLGALSF VDTVCLKSLK NIFHDFREIE VEVYMAACHS PVVSQLEAGH
       730        740        750
FFDASITKKH LFASVHDAVT FALQHPRPVP DSPVSVTRL         10         20         30         40         50         60
MGLADASGPR DTQALLSATQ AMDLRRRDYH MERPLLNQEH LEELGRWGSA PRTHQWRTWL
        70         80         90        100        110        120
QCSRARAYAL LLQHLPVLVW LPRYPVRDWL LGDLLSGLSV AIMQLPQGLA YALLAGLPPV
       130        140        150        160        170        180
FGLYSSFYPV FIYFLFGTSR HISVGTFAVM SVMVGSVTES LAPQALNDSM INETARDAAR
       190        200        210        220        230        240
VQVASTLSVL VGLFQVGLGL IHFGFVVTYL SEPLVRGYTT AAAVQVFVSQ LKYVFGLHLS
       250        260        270        280        290        300
SHSGPLSLIY TVLEVCWKLP QSKVGTVVTA AVAGVVLVVV KLLNDKLQQQ LPMPIPGELL
       310        320        330        340        350        360
TLIGATGISY GMGLKHRFEV DVVGNIPAGL VPPVAPNTQL FSKLVGSAFT IAVVGFAIAI
       370        380        390        400        410        420
SLGKIFALRH GYRVDSNQEL VALGLSNLIG GIFQCFPVSC SMSRSLVQES TGGNSQVAGA
       430        440        450        460        470        480
ISSLFILLII VKLGELFHDL PKAVLAAIII VNLKGMLRQL SDMRSLWKAN RADLLIWLVT
       490        500        510        520        530        540
FTATILLNLD LGLVVAVIFS LLLVVVRTQM PHYSVLGQVP DTDIYRDVAE YSEAKEVRGV
       550        560        570        580        590        600
KVFRSSATVY FANAEFYSDA LKQRCGVDVD FLISQKKKLL KKQEQLKLKQ LQKEEKLRKQ
       610        620        630        640        650        660
AASPKGASVS INVNTSLEDM RSNNVEDCKM MQVSSGDKME DATANGQEDS KAPDGSTLKA
       670        680        690        700        710        720
LGLPQPDFHS LILDLGALSF VDTVCLKSLK NIFHDFREIE VEVYMAACHS PVVSQLEAGH
       730        740        750
FFDASITKKH LFASVHDAVT FALQHPRPVP DSPVSVTRL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9BXS9-1-unknown	MGLADA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9BXS9-1-unknown	MGLADA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88613
Q9BXS9-1-unknown	MGLADA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88614
Q9BXS9-2-	GLADAS...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_CD95	23264352
Q9BXS9-2-	GLADAS...	2		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9BXS9-2-	GLADAS...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9BXS9-2-	GLADAS...	2		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9BXS9-2-unknown	GLADAS...	2		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9BXS9-2-unknown	GLADAS...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160242
Q9BXS9-2-unknown	GLADAS...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160243
Q9BXS9-22-unknown	MDLRRR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88615
Q9BXS9-22-unknown	MDLRRR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88616
Q9BXS9-22-unknown	MDLRRR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88617
Q9BXS9-22-unknown	MDLRRR...	22	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000351597
Q9BXS9-22-unknown	MDLRRR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98092
Q9BXS9-22-unknown	MDLRRR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98093
Q9BXS9-155-unknown	GSVTES...	155	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000389922
Q9BXS9-155-unknown	GSVTES...	155	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt129518
Q9BXS9-155-unknown	GSVTES...	155	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt129519
Q9BXS9-155-unknown	GSVTES...	155	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt129520
Q9BXS9-155-unknown	GSVTES...	155	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt129516
Q9BXS9-155-unknown	GSVTES...	155	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt129517

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LGLVVA	495	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000389922
...LGLVVA	495	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107854
...LGLVVA	495	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107853
...LGLVVA	495	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107855
...LGLVVA	495	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107851
...LGLVVA	495	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107852
...SVTRL	759	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SVTRL	759	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84234
...SVTRL	759	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84233
...SVTRL	759	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84231
...SVTRL	759	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84232

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)