Q9CQ65: S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}

General Information

Protein names	- S-methyl-5'-thioadenosine phosphorylase {ECO:0000255\|HAMAP-Rule:MF_03155} - 2.4.2.28 {ECO:0000255\|HAMAP-Rule:MF_03155} - 5'-methylthioadenosine phosphorylase {ECO:0000255\|HAMAP-Rule:MF_03155} - MTA phosphorylase {ECO:0000255\|HAMAP-Rule:MF_03155} - MTAP {ECO:0000255\|HAMAP-Rule:MF_03155} - MTAPase {ECO:0000255\|HAMAP-Rule:MF_03155}
Gene names	Mtap
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9CQ65

7 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASGSACTAV KIGIIGGTGL DDPEILEGRT EKYVDTPFGK PSDALILGKI KNVDCVLLAR
        70         80         90        100        110        120
HGRQHTIMPS KVNYQANIWA LKEEGCTHVI VTTACGSLRE EIQPGDMVII DQFIDRTSLR
       130        140        150        160        170        180
PQTFYDGSHC SARGVCHIPM AEPFCPKTRE VLIETAKKLG LRCHSKGTIV TIEGPRFSSR
       190        200        210        220        230        240
AESLIFRTWG ADVVNMTTVP EVVLAKEAGI CYASIAMATD YDCWKEHEEA VSVDGVLKTM
       250        260        270        280
KENANKAKSL LLTTIPQIGS MEWSETLRNL KNMAQFSVLP PRH

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9CQ65-1-unknown	MASGSA...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9CQ65-14-unknown	IIGGTG...	14	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34191
Q9CQ65-36-unknown	TPFGKP...	36	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9CQ65-50-unknown	IKNVDC...	50	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34192
Q9CQ65-107-unmodified	MVIIDQ...	107		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q9CQ65-124-unknown	FYDGSH...	124	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34193
Q9CQ65-261-unknown	MEWSET...	261	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34194

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AVKIGI	13	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34191
...LILGKI	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34192
...LRPQTF	123	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34193
...PQIGSM	260	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34194
...LPPRH	283	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	13	KIGI.\|.IIGG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	49	LGKI.\|.IKNV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	123	PQTF.\|.FYDG	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP2_MOUSE	260	IGSM.\|.MEWS	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)