Q9D554: Splicing factor 3A subunit 3

General Information

Protein names	- Splicing factor 3A subunit 3 - SF3a60 - Spliceosome-associated protein 61 - SAP 61
Gene names	Sf3a3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9D554

10 N-termini

9 C-termini

9 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
METILEQQRR YHEEKERLMD VMAKEMLTKK STLRDQINSD HRTRAMQDRY MEVSGNLRDL
        70         80         90        100        110        120
YDDKDGLRKE ELNAISGPNE FAEFYNRLKQ IKEFHRKHPN EICVPMSVEF EELLKARENP
       130        140        150        160        170        180
SEEAQNLVEF TDEEGYGRYL DLHDCYLKYI NLKASEKLDY ITYLSIFDQL FDIPKERKNA
       190        200        210        220        230        240
EYKRYLEMLL EYLQDYTDRV KPLQDQNELF GKIQTDFEKK WDNGTFPGWP KETSSALTHA
       250        260        270        280        290        300
GAHLDLSAFS SWEELASLGL DRLKSALLAL GLKCGGTLEE RAQRLFSTKG KSLESLDTSL
       310        320        330        340        350        360
FAKNPKSKGT KRDTERNKDI AFLEAQIYEY VEILGEQRQL THENVQRKQA RTGEEREEEE
       370        380        390        400        410        420
EEQISESESE DEENEIIYNP KNLPLGWDGK PIPYWLYKLH GLNINYNCEI CGNYTYRGPK
       430        440        450        460        470        480
AFQRHFAEWR HAHGMRCLGI PNTAHFANVT QIEDAVSLWA KLKLQKASER WQPDTEEEYE
       490        500
DSSGNVVNKK TYEDLKRQGL L

Isoforms

Sequence View

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Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

10 N-termini - 9 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9D554-1-Acetylation	METILE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9D554-23-unknown	AKEMLT...	23		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31079
Q9D554-27-unknown	LTKKST...	27		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31080
Q9D554-72-unknown	LNAISG...	72		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34250
Q9D554-75-unknown	ISGPNE...	75		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34251
Q9D554-90-unknown	QIKEFH...	90		inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9D554-106-unknown	MSVEFE...	106		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34252
Q9D554-108-unknown	VEFEEL...	108		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34253
Q9D554-127-unknown	LVEFTD...	127		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34254
Q9D554-301-unknown	FAKNPK...	301		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31081
Q9D554-301-unknown	FAKNPK...	301		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29358

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LMDVMA	22	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31079
...MAKEML	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31080
...LRKEEL	71	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34250
...EELNAI	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34251
...EICVPM	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34252
...CVPMSV	107	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34253
...EEAQNL	126	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34254
...LDTSLF	300	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31081
...LDTSLF	300	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29358
...RQGLL	501	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	22	DVMA.\|.AKEM	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SF3A3_MOUSE @22
CATE_MOUSE	26	KEML.\|.LTKK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SF3A3_MOUSE @26
MMP2_MOUSE	71	KEEL.\|.LNAI	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	74	LNAI.\|.ISGP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	105	CVPM.\|.MSVE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	107	PMSV.\|.VEFE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	126	AQNL.\|.LVEF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	300	TSLF.\|.FAKN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> SF3A3_MOUSE @300
CATD_MOUSE	300	TSLF.\|.FAKN	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> SF3A3_MOUSE @300

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)