Q9D753: Exosome complex component RRP43

General Information

Protein names	- Exosome complex component RRP43 - Exosome component 8 - Ribosomal RNA-processing protein 43
Gene names	Exosc8
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9D753

5 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAGFKTVEP LEYYRRFLKE NCRPDGRELG EFRATTVNIG SISTADGSAL VKLGNTTVIC
        70         80         90        100        110        120
GVKAEFAAPP VDAPDRGYVV PNVDLPPLCS SRFRTGPPGE EAQVTSQFIA DVVDNSQVIK
       130        140        150        160        170        180
KEDLCISPGK LAWVLYCDLI CLDYDGNILD ACTFALLAAL KNVQLPEVTI NEETALAEVN
       190        200        210        220        230        240
LKKKSYLNVR TNPVATSFAV FDDTLLIVDP TGEEEHLSTG TLTVVTDEDG KLCCLHKPGG
       250        260        270
SGLTGAKLQD CMSRAVTRHK EVSKLLDEVI QSMRHK

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9D753-2-unknown	MAAGFK...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9D753-2-unknown	MAAGFK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9D753-2-Acetylation	AAGFKT...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9D753-2-Acetylation	AAGFKT...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q9D753-2-Acetylation	AAGFKT...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9D753-5-unknown	FKTVEP...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34259
Q9D753-7-unmodified	TVEPLE...	7			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q9D753-19-unknown	KENCRP...	19		inferred from electronic annotation	unknown	TISdb		inferred from TISdb

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...EDLCIS	126	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000118780
	...SMRHK	276	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	4	AAGF.\|.FKTV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)