Q9D8Y0: EF-hand domain-containing protein D2

General Information

Protein names	- EF-hand domain-containing protein D2 - Swiprosin-1
Gene names	Efhd2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9D8Y0

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATDELASKL SRRLQMEGEG GEATEQPGLN GAAAAAAAEA PDETAQALGS ADDELSAKLL
        70         80         90        100        110        120
RRADLNQGIG EPQSPSRRVF NPYTEFKEFS RKQIKDMEKM FKQYDAGRDG FIDLMELKLM
       130        140        150        160        170        180
MEKLGAPQTH LGLKSMIQEV DEDFDSKLSF REFLLIFRKA AAGELQEDSG LQVLARLSEI
       190        200        210        220        230        240
DVSTEGVKGA KNFFEAKVQA INVSSRFEEE IKAEQEERKK QAEEVKQRKA AFKELQSTFK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9D8Y0-2-unknown	MATDEL...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9D8Y0-2-unknown	MATDEL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9D8Y0-2-Acetylation	ATDELA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9D8Y0-2-Acetylation	ATDELA...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q9D8Y0-2-Acetylation	ATDELA...	2	acetylation-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
Q9D8Y0-2-Acetylation	ATDELA...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9D8Y0-62-unmodified	RADLNQ...	62			N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q9D8Y0-65-unknown	LNQGIG...	65		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34267

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...LRRADL	64	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34267
	...QSTFK	240	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	64	RADL.\|.LNQG	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)