Q9DBR7: Protein phosphatase 1 regulatory subunit 12A
Protein names | - Protein phosphatase 1 regulatory subunit 12A - Myosin phosphatase-targeting subunit 1 - Myosin phosphatase target subunit 1 |
---|---|
Gene names | Ppp1r12a |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9DBR7 |
9
N-termini
7
C-termini
6
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MKMADAKQKR NEQLKRWIGS ETDLEPPVVK RQKTKVKFDD GAVFLAACSS GDTDEVLKLL
70 80 90 100 110 120
HRGADINYAN VDGLTALHQA CIDDNVDMVK FLVENGANIN QPDNEGWIPL HAAASCGYLD
130 140 150 160 170 180
IAEFLIGQGA HVGAVNSEGD TPLDIAEEEA MEELLQNEVN RQGVDIEAAR KEEERVMLRD
190 200 210 220 230 240
ARQWLNSGHI SDVRHAKSGG TALHVAAAKG YTEVLKLLIQ AGYDVNIKDY DGWTPLHAAA
250 260 270 280 290 300
HWGKEEACRI LVDNLCDMET VNKVGQTAFD VADEDILGYL EELQKKQTLL HSEKRDKKSP
310 320 330 340 350 360
LIESTANMEN NQPQKAFKNK ETLIIEPEKN ASRIESLEHE KADEEEEGKK DESSCSSEED
370 380 390 400 410 420
EEDDSESEAE TDKTKPMASV SNAHTSSTQA APAAVTAPTL SSNQGTPTSP VKKFPISTTK
430 440 450 460 470 480
ISPKEEERKD ESPASWRLGL RKTGSYGALA EISASKEAQK EKDTAGVMRS ASSPRLSSSL
490 500 510 520 530 540
DNKEKEKDNK GTRLAYVTPT IPRRLASTSD IEEKENRESS SLRTSSSYTR RKWEDDLKKN
550 560 570 580 590 600
SSINEGSTYH RSCSFGRRQD DLISCSVPST TSTPTVTSAA GLQRSLPSST STAAKTPPGS
610 620 630 640 650 660
SSAGTQSSTS NRLWAEDSTE KEKDSAPTAV TIPVAPTVVN AAAPSTTTLT TTTAGTVSEV
670 680 690 700 710 720
RERRRSYLTP VRDEESESQR KARSRQARQS RRSTQGVTLT DLQEAEKTIG RSRSTRTREQ
730 740 750 760 770 780
ENEEKEKEEK EKQDKEKQEE KKESEASRED EYKQKYSRTY DETYTRYRPV STSSSSAPSS
790 800 810 820 830 840
SSLSTLGSTL YASSQLNRPN SLVGITSAYS RGLAKENERE GEKKEEEKEG EDKSQPKSIR
850 860 870 880 890 900
ERRRPREKRR STGVSFWTQD SDENEQERQS DTEDGSSKRE TQTDSVSRYD SSSTSSSDRY
910 920 930 940 950 960
DSLLGRSASY SYLEDRKPYS SRLEKDDSTD FKKLYEQILA ENEKLKAQLH DTNMELTDLK
970 980 990 1000 1010 1020
LQLEKATQRQ ERFADRSQLE MEKRERRALE RRISEMEEEL KMLPDLKADN QRLKDENGAL
IRVISKLSK
Isoforms
- Isoform 2 of Protein phosphatase 1 regulatory subunit 12ASequence View
10 20 30 40 50 60
MKMADAKQKR NEQLKRWIGS ETDLEPPVVK RQKTKVKFDD GAVFLAACSS GDTDEVLKLL
70 80 90 100 110 120
HRGADINYAN VDGLTALHQA CIDDNVDMVK FLVENGANIN QPDNEGWIPL HAAASCGYLD
130 140 150 160 170 180
IAEFLIGQGA HVGAVNSEGD TPLDIAEEEA MEELLQNEVN RQGVDIEAAR KEEERVMLRD
190 200 210 220 230 240
ARQWLNSGHI SDVRHAKSGG TALHVAAAKG YTEVLKLLIQ AGYDVNIKDY DGWTPLHAAA
250 260 270 280 290 300
HWGKEEACRI LVDNLCDMET VNKVGQTAFD VADEDILGYL EELQKKQTLL HSEKRDKKSP
310 320 330 340 350 360
LIESTANMEN NQPQKAFKNK ETLIIEPEKN ASRIESLEHE KADEEEEGKK DESSCSSEED
370 380 390 400 410 420
EEDDSESEAE TDKTKPMASV SNAHTSSTQA APAAVTAPTL SSNQGTPTSP VKKFPISTTK
430 440 450 460 470 480
ISPKEEERKD ESPASWRLGL RKTGSYGALA EISASKEAQK EKDTAGVMRS ASSPRLSSSL
490 500 510 520 530 540
DNKEKEKDNK GTRLAYVTPT IPRRLASTSD IEEKENRESS SLRTSSSYTR RKWEDDLKKN
550 560 570 580 590 600
SSINEGSTYH RSCSFGRRQD DLISCSVPST TSTPTVTSAA GLQRSLPSST STAAKTPPGS
610 620 630 640 650 660
SSAGTQSSTS NRLWAEDSTE KEKDSAPTAV TIPVAPTVVN AAAPSTTTLT TTTAGTVSEV
670 680 690 700 710 720
RERRRSYLTP VRDEESESQR KARSRQARQS RRSTQGVTLT DLQEAEKTIG RSRSTRTREQ
730 740 750 760 770 780
ENEEKEKEEK EKQDKEKQEE KKESEASRED EYKQKYSRTY DETYTRYRPV STSSSSAPSS
790 800 810 820 830 840
SSLSTLGSTL YASSQLNRPN SLVGITSAYS RGLAKENERE GEKKEEEKEG EDKSQPKSIR
850 860 870 880 890 900
ERRRPREKRR STGVSFWTQD SDENEQERQS DTEDGSSKRE TQTDSVSRYD SSSTSSSDRY
910 920 930 940 950 960
DSLLGRSASY SYLEDRKPYS SRLEKDDSTD FKKLYEQILA ENEKLKAQLH DTNMELTDLK
970 980 990 1000 1010 1020
LQLEKATQRQ ERFADRSQLE MEKRERRALE RRISEMEEEL KMLPDLKADN QRLKDENGAL
IRVISKLSK
Protein Neighborhood
Domains & Features
9 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9DBR7-1-unknown | MKMADA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9DBR7-1-unknown | MKMADA... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt82106 | |||
Q9DBR7-17-unknown | WIGSET... | 17 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34280 | |||
Q9DBR7-17-unknown | WIGSET... | 17 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt136670 | |||
Q9DBR7-45-unknown | LAACSS... | 45 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34282 | |||
Q9DBR7-45-unknown | LAACSS... | 45 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt138784 | |||
Q9DBR7-319-unknown | NKETLI... | 319 | N-TAILS | Overall CM. | auf dem Keller U.: A statistics-based platform for quantitative N-terminome... | 20305283 | |||
Q9DBR7-319-unknown | NKETLI... | 319 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160481 | |||
Q9DBR7-505-unknown | LASTSD... | 505 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34284 | |||
Q9DBR7-505-unknown | LASTSD... | 505 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153480 | |||
Q9DBR7-697-unknown | VTLTDL... | 697 | N-TAILS | Overall CM. | auf dem Keller U.: A statistics-based platform for quantitative N-terminome... | 20305283 | |||
Q9DBR7-697-unknown | VTLTDL... | 697 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160516 | |||
Q9DBR7-802-unknown | LVGITS... | 802 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34286 | |||
Q9DBR7-802-unknown | LVGITS... | 802 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156495 | |||
Q9DBR7-803-unknown | VGITSA... | 803 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31113 | |||
Q9DBR7-803-unknown | VGITSA... | 803 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156498 | |||
Q9DBR7-857-unknown | WTQDSD... | 857 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34288 | |||
Q9DBR7-857-unknown | WTQDSD... | 857 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt156703 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...EQLKRW | 16 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34280 | |||
...DGAVFL | 44 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34282 | |||
...DGAVFL | 44 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt121839 | |||
...TIPRRL | 504 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34284 | |||
...TIPRRL | 504 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136903 | |||
...NRPNSL | 801 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34286 | |||
...NRPNSL | 801 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139979 | |||
...RPNSLV | 802 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31113 | |||
...RPNSLV | 802 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt139982 | |||
...TGVSFW | 856 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34288 | |||
...TGVSFW | 856 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt140190 | |||
...SKLSK | 1029 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MMP2_MOUSE | 16 | LKRW.|.WIGS | inferred from experiment | unknown | MEROPS | Overall CM | auf dem Keller U et al.:A statistics-based platform for... (M10.003) | 20305283, |
MMP2_MOUSE | 44 | AVFL.|.LAAC | inferred from experiment | unknown | MEROPS | Overall CM | auf dem Keller U et al.:A statistics-based platform for... (M10.003) | 20305283, |
MMP2_MOUSE | 504 | PRRL.|.LAST | inferred from experiment | unknown | MEROPS | Overall CM | Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) | 20305284, |
MMP2_MOUSE | 801 | PNSL.|.LVGI | inferred from experiment | unknown | MEROPS | Overall CM | Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) | 20305284, |
CATE_MOUSE | 802 | NSLV.|.VGIT | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> MYPT1_MOUSE @802 | ||
MMP2_MOUSE | 856 | VSFW.|.WTQD | inferred from experiment | unknown | MEROPS | Overall CM | auf dem Keller U et al.:A statistics-based platform for... (M10.003) | 20305283, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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