Q9GZP0: Platelet-derived growth factor D

General Information

Protein names	- Platelet-derived growth factor D - PDGF-D - Iris-expressed growth factor - Spinal cord-derived growth factor B - SCDGF-B - Platelet-derived growth factor D, latent form - PDGFD latent form - Platelet-derived growth factor D, receptor-binding form - PDGFD receptor-binding form
Gene names	PDGFD
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9GZP0

4 N-termini

2 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MHRLIFVYTL ICANFCSCRD TSATPQSASI KALRNANLRR DESNHLTDLY RRDETIQVKG
        70         80         90        100        110        120
NGYVQSPRFP NSYPRNLLLT WRLHSQENTR IQLVFDNQFG LEEAENDICR YDFVEVEDIS
       130        140        150        160        170        180
ETSTIIRGRW CGHKEVPPRI KSRTNQIKIT FKSDDYFVAK PGFKIYYSLL EDFQPAAASE
       190        200        210        220        230        240
TNWESVTSSI SGVSYNSPSV TDPTLIADAL DKKIAEFDTV EDLLKYFNPE SWQEDLENMY
       250        260        270        280        290        300
LDTPRYRGRS YHDRKSKVDL DRLNDDAKRY SCTPRNYSVN IREELKLANV VFFPRCLLVQ
       310        320        330        340        350        360
RCGGNCGCGT VNWRSCTCNS GKTVKKYHEV LQFEPGHIKR RGRAKTMALV DIQLDHHERC
       370
DCICSSRPPR

Isoforms

- Isoform 2 of Platelet-derived growth factor D

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9GZP0-1-unknown	MHRLIF...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84738
Q9GZP0-19-unknown	RDTSAT...	19	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9GZP0-19-unknown	RDTSAT...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112131
Q9GZP0-250-unknown	SYHDRK...	250	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9GZP0-250-unknown	SYHDRK...	250	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt116094
Q9GZP0-258-unknown	VDLDRL...	258	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26655
Q9GZP0-258-unknown	VDLDRL...	258	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26925
Q9GZP0-258-unknown	VDLDRL...	258	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27223
Q9GZP0-258-unknown	VDLDRL...	258	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9823
Q9GZP0-258-unknown	VDLDRL...	258	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27075
Q9GZP0-258-unknown	VDLDRL...	258	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27370
Q9GZP0-258-unknown	VDLDRL...	258	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt148466

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DRKSKV	257	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26655
...DRKSKV	257	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26925
...DRKSKV	257	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27223
...DRKSKV	257	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9823
...DRKSKV	257	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27075
...DRKSKV	257	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27370
...DRKSKV	257	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt131839
...SRPPR	370	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SRPPR	370	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80356

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
NEC2_HUMAN	257	KSKV.\|.VDLD	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
PCSK4_HUMAN	257	KSKV.\|.VDLD	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
PCSK6_HUMAN	257	KSKV.\|.VDLD	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
FURIN_HUMAN	257	KSKV.\|.VDLD	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
PCSK5_HUMAN	257	KSKV.\|.VDLD	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
PCSK7_HUMAN	257	KSKV.\|.VDLD	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)