Q9H6P5: Threonine aspartase 1

General Information

Protein names	- Threonine aspartase 1 - Taspase-1 - 3.4.25.- - Threonine aspartase subunit alpha - Threonine aspartase subunit beta
Gene names	TASP1
Organism	Homo sapiens
Protease Family	T02.004
Protease ID	T02.004
Chromosome location
UniProt ID	Q9H6P5

2 N-termini

3 C-termini

1 Cleavages

9 Substrates

Sequence

        10         20         30         40         50         60
MTMEKGMSSG EGLPSRSSQV SAGKITAKEL ETKQSYKEKR GGFVLVHAGA GYHSESKAKE
        70         80         90        100        110        120
YKHVCKRACQ KAIEKLQAGA LATDAVTAAL VELEDSPFTN AGMGSNLNLL GEIECDASIM
       130        140        150        160        170        180
DGKSLNFGAV GALSGIKNPV SVANRLLCEG QKGKLSAGRI PPCFLVGEGA YRWAVDHGIP
       190        200        210        220        230        240
SCPPNIMTTR FSLAAFKRNK RKLELAERVD TDFMQLKKRR QSSEKENDSG TLDTVGAVVV
       250        260        270        280        290        300
DHEGNVAAAV SSGGLALKHP GRVGQAALYG CGCWAENTGA HNPYSTAVST SGCGEHLVRT
       310        320        330        340        350        360
ILARECSHAL QAEDAHQALL ETMQNKFISS PFLASEDGVL GGVIVLRSCR CSAEPDSSQN
       370        380        390        400        410        420
KQTLLVEFLW SHTTESMCVG YMSAQDGKAK THISRLPPGA VAGQSVAIEG GVCRLESPVN

Isoforms

- Isoform 2 of Threonine aspartase 1 - Isoform 3 of Threonine aspartase 1

Sequence View

        10         20         30         40         50         60
MTMEKGMSSG EGLPSRSSQV SAGKITAKEL ETKQSYKEKR GGFVLVHAGA GYHSESKAKE
        70         80         90        100        110        120
YKHVCKRACQ KAIEKLQAGA LATDAVTAAL VELEDSPFTN AGMGSNLNLL GEIECDASIM
       130        140        150        160        170        180
DGKSLNFGAV GALSGIKNPV SVANRLLCEG QKGKLSAGRI PPCFLVGEGA YRWAVDHGIP
       190        200        210        220        230        240
SCPPNIMTTR FSLAAFKRNK RKLELAERVD TDFMQLKKRR QSSEKENDSG TLDTVGAVVV
       250        260        270        280        290        300
DHEGNVAAAV SSGGLALKHP GRVGQAALYG CGCWAENTGA HNPYSTAVST SGCGEHLVRT
       310        320        330        340        350        360
ILARECSHAL QAEDAHQALL ETMQNKFISS PFLASEDGVL GGVIVLRSCR CSAEPDSSQN
       370        380        390        400        410        420
KQTLLVEFLW SHTTESMCVG YMSAQDGKAK THISRLPPGA VAGQSVAIEG GVCRLESPVN

        10         20         30         40         50         60
MTMEKGMSSG EGLPSRSSQV SAGKITAKEL ETKQSYKEKR GGFVLVHAGA GYHSESKAKE
        70         80         90        100        110        120
YKHVCKRACQ KAIEKLQAGA LATDAVTAAL VELEDSPFTN AGMGSNLNLL GEIECDASIM
       130        140        150        160        170        180
DGKSLNFGAV GALSGIKNPV SVANRLLCEG QKGKLSAGRI PPCFLVGEGA YRWAVDHGIP
       190        200        210        220        230        240
SCPPNIMTTR FSLAAFKRNK RKLELAERVD TDFMQLKKRR QSSEKENDSG TLDTVGAVVV
       250        260        270        280        290        300
DHEGNVAAAV SSGGLALKHP GRVGQAALYG CGCWAENTGA HNPYSTAVST SGCGEHLVRT
       310        320        330        340        350        360
ILARECSHAL QAEDAHQALL ETMQNKFISS PFLASEDGVL GGVIVLRSCR CSAEPDSSQN
       370        380        390        400        410        420
KQTLLVEFLW SHTTESMCVG YMSAQDGKAK THISRLPPGA VAGQSVAIEG GVCRLESPVN

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9H6P5-1-unknown	MTMEKG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9H6P5-234-unknown	TVGAVV...	234	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9H6P5-234-unknown	TVGAVV...	234	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31677

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SGTLDT	233	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...SGTLDT	233	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31677
...QNKFIS	328	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400580
...ESPVN	420	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
TASP1_HUMAN	233	TLDT.\|.TVGA	inferred from experiment	unknown	MEROPS	Tong L	Khan JA et al.:Crystal structure of human Tasp... (T02.004)	16216576,
TF2AA-Isoform2_HUMAN	235	QVDG.\|.GTGD	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC31669
TF2AA_HUMAN	274	QVDG.\|.GTGD	inferred from experiment	unknown	MEROPS	Stunnenberg HG	Zhou H et al.:Uncleaved TFIIA is a substrate ... (T02.004)	16537915,
KMT2A-Isoform2_HUMAN	2628	QVDG.\|.GADD	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC31671
KMT2A_HUMAN	2666	QVDG.\|.GADD	inferred from experiment	unknown	MEROPS	Stunnenberg HG	Zhou H et al.:Uncleaved TFIIA is a substrate ... (T02.004)	16537915,
KMT2A-Isoform3_HUMAN	2669	QVDG.\|.GADD	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC31671
KMT2A-Isoform2_HUMAN	2680	QLDG.\|.GVDD	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC31674
KMT2A_HUMAN	2718	QLDG.\|.GVDD	inferred from experiment	unknown	MEROPS	Korsmeyer SJ	Hsieh JJ et al.:Taspase1: a threonine aspartase... (T02.004)	14636557,
KMT2A-Isoform3_HUMAN	2721	QLDG.\|.GVDD	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC31674

TopFIND

Q9H6P5: Threonine aspartase 1

General Information

2

N-termini

3

C-termini

1

Cleavages

9

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 9 Substrates

N-termini

C-termini

Cleavages

Substrates