Q9HCC0: Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

General Information

Protein names	- Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial - MCCase subunit beta - 6.4.1.4 {ECO:0000269\|PubMed:17360195} - 3-methylcrotonyl-CoA carboxylase 2 - 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit - 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta
Gene names	MCCC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9HCC0

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MWAVLRLALR PCARASPAGP RAYHGDSVAS LGTQPDLGSA LYQENYKQMK ALVNQLHERV
        70         80         90        100        110        120
EHIKLGGGEK ARALHISRGK LLPRERIDNL IDPGSPFLEL SQFAGYQLYD NEEVPGGGII
       130        140        150        160        170        180
TGIGRVSGVE CMIIANDATV KGGAYYPVTV KKQLRAQEIA MQNRLPCIYL VDSGGAYLPR
       190        200        210        220        230        240
QADVFPDRDH FGRTFYNQAI MSSKNIAQIA VVMGSCTAGG AYVPAMADEN IIVRKQGTIF
       250        260        270        280        290        300
LAGPPLVKAA TGEEVSAEDL GGADLHCRKS GVSDHWALDD HHALHLTRKV VRNLNYQKKL
       310        320        330        340        350        360
DVTIEPSEEP LFPADELYGI VGANLKRSFD VREVIARIVD GSRFTEFKAF YGDTLVTGFA
       370        380        390        400        410        420
RIFGYPVGIV GNNGVLFSES AKKGTHFVQL CCQRNIPLLF LQNITGFMVG REYEAEGIAK
       430        440        450        460        470        480
DGAKMVAAVA CAQVPKITLI IGGSYGAGNY GMCGRAYSPR FLYIWPNARI SVMGGEQAAN
       490        500        510        520        530        540
VLATITKDQR AREGKQFSSA DEAALKEPII KKFEEEGNPY YSSARVWDDG IIDPADTRLV
       550        560
LGLSFSAALN APIEKTDFGI FRM

Isoforms

- Isoform 2 of Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

Sequence View

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Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9HCC0-1-unknown	MWAVLR...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt80597
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q9HCC0-23-	YHGDSV...	23		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9HCC0-23-unknown	YHGDSV...	23	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9HCC0-23-unknown	YHGDSV...	23	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt113376

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...GIFRM	563	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...GIFRM	563	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt76215

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)