Q9NPL8: Complex I assembly factor TIMMDC1, mitochondrial

General Information

Protein names	- Complex I assembly factor TIMMDC1, mitochondrial - Protein M5-14 - Translocase of inner mitochondrial membrane domain-containing protein 1 - TIMM domain containing-protein 1
Gene names	TIMMDC1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NPL8

4 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEVPPPAPRS FLCRALCLFP RVFAAEAVTA DSEVLEERQK RLPYVPEPYY PESGWDRLRE
        70         80         90        100        110        120
LFGKDEQQRI SKDLANICKT AATAGIIGWV YGGIPAFIHA KQQYIEQSQA EIYHNRFDAV
       130        140        150        160        170        180
QSAHRAATRG FIRYGWRWGW RTAVFVTIFN TVNTSLNVYR NKDALSHFVI AGAVTGSLFR
       190        200        210        220        230        240
INVGLRGLVA GGIIGALLGT PVGGLLMAFQ KYSGETVQER KQKDRKALHE LKLEEWKGRL
       250        260        270        280
QVTEHLPEKI ESSLQEDEPE NDAKKIEALL NLPRNPSVID KQDKD

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NPL8-1-unknown	MEVPPP...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NPL8-25-	AEAVTA...	25		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9NPL8-25-	AEAVTA...	25		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9NPL8-25-	AEAVTA...	25		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9NPL8-25-	AEAVTA...	25		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q9NPL8-25-	AEAVTA...	25		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9NPL8-27-	AVTADS...	27		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9NPL8-28-	VTADSE...	28		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9NPL8-28-	VTADSE...	28		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...LKLEEW	235	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000420122
	...KQDKD	285	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)