Q9P2E9: Ribosome-binding protein 1

General Information

Protein names	- Ribosome-binding protein 1 - 180 kDa ribosome receptor homolog - RRp - ES/130-related protein - Ribosome receptor protein
Gene names	RRBP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9P2E9

37 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 1 of Ribosome-binding protein 1 - Isoform 2 of Ribosome-binding protein 1

Sequence View

        10         20         30         40         50         60
MDIYDTQTLG VVVFGGFMVV SAIGIFLVST FSMKETSYEE ALANQRKEMA KTHHQKVEKK
        70         80         90        100        110        120
KKEKTVEKKG KTKKKEEKPN GKIPDHDPAP NVTVLLREPV RAPAVAVAPT PVQPPIIVAP
       130        140        150        160        170        180
VATVPAMPQE KLASSPKDKK KKEKKVAKVE PAVSSVVNSI QVLTSKAAIL ETAPKEVPMV
       190        200        210        220        230        240
VVPPVGAKGN TPATGTTQGK KAEGTQNQSK KAEGAPNQGR KAEGTPNQGK KTEGTPNQGK
       250        260        270        280        290        300
KAEGTPNQGK KAEGTPNQGK KAEGAQNQGK KVDTTPNQGK KVEGAPTQGR KAEGAQNQAK
       310        320        330        340        350        360
KVEGAQNQGK KAEGAQNQGK KGEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK
       370        380        390        400        410        420
KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KVEGAQNQGK KAEGAQNQGK KAEGAQNQGK
       430        440        450        460        470        480
KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KVEGAQNQGK
       490        500        510        520        530        540
KAEGAQNQGK KAEGAQNQGK KAEGAQNQGQ KGEGAQNQGK KTEGAQGKKA ERSPNQGKKG
       550        560        570        580        590        600
EGAPIQGKKA DSVANQGTKV EGITNQGKKA EGSPSEGKKA EGSPNQGKKA DAAANQGKKT
       610        620        630        640        650        660
ESASVQGRNT DVAQSPEAPK QEAPAKKKSG SKKKGEPGPP DADGPLYLPY KTLVSTVGSM
       670        680        690        700        710        720
VFNEGEAQRL IEILSEKAGI IQDTWHKATQ KGDPVAILKR QLEEKEKLLA TEQEDAAVAK
       730        740        750        760        770        780
SKLRELNKEM AAEKAKAAAG EAKVKKQLVA REQEITAVQA RMQASYREHV KEVQQLQGKI
       790        800        810        820        830        840
RTLQEQLENG PNTQLARLQQ ENSILRDALN QATSQVESKQ NAELAKLRQE LSKVSKELVE
       850        860        870        880        890        900
KSEAVRQDEQ QRKALEAKAA AFEKQVLQLQ ASHRESEEAL QKRLDEVSRE LCHTQSSHAS
       910        920        930        940        950        960
LRADAEKAQE QQQQMAELHS KLQSSEAEVR SKCEELSGLH GQLQEARAEN SQLTERIRSI
       970        980        990       1000       1010       1020
EALLEAGQAR DAQDVQASQA EADQQQTRLK ELESQVSGLE KEAIELREAV EQQKVKNNDL
      1030       1040       1050       1060       1070       1080
REKNWKAMEA LATAEQACKE KLLSLTQAKE ESEKQLCLIE AQTMEALLAL LPELSVLAQQ
      1090       1100       1110       1120       1130       1140
NYTEWLQDLK EKGPTLLKHP PAPAEPSSDL ASKLREAEET QSTLQAECDQ YRSILAETEG
      1150       1160       1170       1180       1190       1200
MLRDLQKSVE EEEQVWRAKV GAAEEELQKS RVTVKHLEEI VEKLKGELES SDQVREHTSH
      1210       1220       1230       1240       1250       1260
LEAELEKHMA AASAECQNYA KEVAGLRQLL LESQSQLDAA KSEAQKQSDE LALVRQQLSE
      1270       1280       1290       1300       1310       1320
MKSHVEDGDI AGAPASSPEA PPAEQDPVQL KTQLEWTEAI LEDEQTQRQK LTAEFEEAQT
      1330       1340       1350       1360       1370       1380
SACRLQEELE KLRTAGPLES SETEEASQLK ERLEKEKKLT SDLGRAATRL QELLKTTQEQ
      1390       1400       1410
LAREKDTVKK LQEQLEKAED GSSSKEGTSV         10         20         30         40         50         60
MDIYDTQTLG VVVFGGFMVV SAIGIFLVST FSMKETSYEE ALANQRKEMA KTHHQKVEKK
        70         80         90        100        110        120
KKEKTVEKKG KTKKKEEKPN GKIPDHDPAP NVTVLLREPV RAPAVAVAPT PVQPPIIVAP
       130        140        150        160        170        180
VATVPAMPQE KLASSPKDKK KKEKKVAKVE PAVSSVVNSI QVLTSKAAIL ETAPKEVPMV
       190        200        210        220        230        240
VVPPVGAKGN TPATGTTQGK KAEGTQNQSK KAEGAPNQGR KAEGTPNQGK KTEGTPNQGK
       250        260        270        280        290        300
KAEGTPNQGK KAEGTPNQGK KAEGAQNQGK KVDTTPNQGK KVEGAPTQGR KAEGAQNQAK
       310        320        330        340        350        360
KVEGAQNQGK KAEGAQNQGK KGEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK
       370        380        390        400        410        420
KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KVEGAQNQGK KAEGAQNQGK KAEGAQNQGK
       430        440        450        460        470        480
KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KVEGAQNQGK
       490        500        510        520        530        540
KAEGAQNQGK KAEGAQNQGK KAEGAQNQGQ KGEGAQNQGK KTEGAQGKKA ERSPNQGKKG
       550        560        570        580        590        600
EGAPIQGKKA DSVANQGTKV EGITNQGKKA EGSPSEGKKA EGSPNQGKKA DAAANQGKKT
       610        620        630        640        650        660
ESASVQGRNT DVAQSPEAPK QEAPAKKKSG SKKKGEPGPP DADGPLYLPY KTLVSTVGSM
       670        680        690        700        710        720
VFNEGEAQRL IEILSEKAGI IQDTWHKATQ KGDPVAILKR QLEEKEKLLA TEQEDAAVAK
       730        740        750        760        770        780
SKLRELNKEM AAEKAKAAAG EAKVKKQLVA REQEITAVQA RMQASYREHV KEVQQLQGKI
       790        800        810        820        830        840
RTLQEQLENG PNTQLARLQQ ENSILRDALN QATSQVESKQ NAELAKLRQE LSKVSKELVE
       850        860        870        880        890        900
KSEAVRQDEQ QRKALEAKAA AFEKQVLQLQ ASHRESEEAL QKRLDEVSRE LCHTQSSHAS
       910        920        930        940        950        960
LRADAEKAQE QQQQMAELHS KLQSSEAEVR SKCEELSGLH GQLQEARAEN SQLTERIRSI
       970        980        990       1000       1010       1020
EALLEAGQAR DAQDVQASQA EADQQQTRLK ELESQVSGLE KEAIELREAV EQQKVKNNDL
      1030       1040       1050       1060       1070       1080
REKNWKAMEA LATAEQACKE KLLSLTQAKE ESEKQLCLIE AQTMEALLAL LPELSVLAQQ
      1090       1100       1110       1120       1130       1140
NYTEWLQDLK EKGPTLLKHP PAPAEPSSDL ASKLREAEET QSTLQAECDQ YRSILAETEG
      1150       1160       1170       1180       1190       1200
MLRDLQKSVE EEEQVWRAKV GAAEEELQKS RVTVKHLEEI VEKLKGELES SDQVREHTSH
      1210       1220       1230       1240       1250       1260
LEAELEKHMA AASAECQNYA KEVAGLRQLL LESQSQLDAA KSEAQKQSDE LALVRQQLSE
      1270       1280       1290       1300       1310       1320
MKSHVEDGDI AGAPASSPEA PPAEQDPVQL KTQLEWTEAI LEDEQTQRQK LTAEFEEAQT
      1330       1340       1350       1360       1370       1380
SACRLQEELE KLRTAGPLES SETEEASQLK ERLEKEKKLT SDLGRAATRL QELLKTTQEQ
      1390       1400       1410
LAREKDTVKK LQEQLEKAED GSSSKEGTSV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

37 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9P2E9-1-unknown	MDIYDT...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9P2E9-1-unknown	MDIYDT...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88216
Q9P2E9-1-unknown	MDIYDT...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88217
Q9P2E9-28-	VSTFSM...	28		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-28-unknown	VSTFSM...	28	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174614
Q9P2E9-28-unknown	VSTFSM...	28	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174615
Q9P2E9-32-unknown	SMKETS...	32		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9P2E9-32-unknown	SMKETS...	32	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160195
Q9P2E9-32-unknown	SMKETS...	32	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160196
Q9P2E9-32-	SMKETS...	32		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9P2E9-104-unknown	AVAVAP...	104	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174574
Q9P2E9-104-unknown	AVAVAP...	104	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174575
Q9P2E9-104-	AVAVAP...	104		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-106-unknown	AVAPTP...	106	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174580
Q9P2E9-106-unknown	AVAPTP...	106	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174581
Q9P2E9-106-	AVAPTP...	106		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-107-	VAPTPV...	107		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-107-unknown	VAPTPV...	107	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174595
Q9P2E9-107-unknown	VAPTPV...	107	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174596
Q9P2E9-167-	AAILET...	167		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-167-	AAILET...	167		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9P2E9-167-unknown	AAILET...	167		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9P2E9-167-unknown	AAILET...	167	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160193
Q9P2E9-808-unknown	ALNQAT...	808	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174589
Q9P2E9-808-unknown	ALNQAT...	808	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174590
Q9P2E9-808-	ALNQAT...	808		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-972-unknown	AQDVQA...	972	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174583
Q9P2E9-972-unknown	AQDVQA...	972	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174584
Q9P2E9-972-	AQDVQA...	972		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-975-	VQASQA...	975		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-975-unknown	VQASQA...	975	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174607
Q9P2E9-975-unknown	VQASQA...	975	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174608
Q9P2E9-1148-	SVEEEE...	1148		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-1148-unknown	SVEEEE...	1148	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174601
Q9P2E9-1148-unknown	SVEEEE...	1148	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174602
Q9P2E9-1239-	AAKSEA...	1239		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9P2E9-1239-unknown	AAKSEA...	1239	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176716
Q9P2E9-1239-unknown	AAKSEA...	1239	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176717
Q9P2E9-1248-	SDELAL...	1248		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-1248-unknown	SDELAL...	1248	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174610
Q9P2E9-1248-unknown	SDELAL...	1248	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174611
Q9P2E9-1263-unknown	SHVEDG...	1263	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174577
Q9P2E9-1263-unknown	SHVEDG...	1263	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174578
Q9P2E9-1263-	SHVEDG...	1263		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-1263-	SHVEDG...	1263		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9P2E9-1268-unknown	GDIAGA...	1268	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174586
Q9P2E9-1268-unknown	GDIAGA...	1268	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174587
Q9P2E9-1268-	GDIAGA...	1268		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-1270-unknown	IAGAPA...	1270	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174592
Q9P2E9-1270-unknown	IAGAPA...	1270	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174593
Q9P2E9-1270-	IAGAPA...	1270		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-1272-	GAPASS...	1272		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-1272-unknown	GAPASS...	1272	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174598
Q9P2E9-1272-unknown	GAPASS...	1272	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174599
Q9P2E9-1299-unknown	AILEDE...	1299	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174286
Q9P2E9-1299-unknown	AILEDE...	1299	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174287
Q9P2E9-1299-	AILEDE...	1299		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9P2E9-1299-	AILEDE...	1299		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-1299-	AILEDE...	1299		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9P2E9-1299-	AILEDE...	1299		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9P2E9-1334-	TAGPLE...	1334		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9P2E9-1334-unknown	TAGPLE...	1334	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174604
Q9P2E9-1334-unknown	TAGPLE...	1334	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174605

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EGTSV	1410	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EGTSV	1410	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83835
...EGTSV	1410	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83834

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)