Q9QUM9: Proteasome subunit alpha type-6

General Information

Protein names	- Proteasome subunit alpha type-6 - 3.4.25.1 {ECO:0000250\|UniProtKB:P60900} - Macropain iota chain - Multicatalytic endopeptidase complex iota chain - Proteasome iota chain
Gene names	Psma6
Organism	Mus musculus
Protease Family
Protease ID	T01.971
Chromosome location
UniProt ID	Q9QUM9

7 N-termini

7 C-termini

6 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSRGSSAGFD RHITIFSPEG RLYQVEYAFK AINQGGLTSV AVRGKDCAVI VTQKKVPDKL
        70         80         90        100        110        120
LDSSTVTHLF KITESIGCVM TGMTADSRSQ VQRARYEAAN WKYKYGYEIP VDMLCKRIAD
       130        140        150        160        170        180
ISQVYTQNAE MRPLGCCMIL IGIDEEQGPQ VYKCDPAGYY CGFKATAAGV KQTESTSFLE
       190        200        210        220        230        240
KKVKKKFDWT FEQTVETAIT CLSTVLSIDF KPSEIEVGVV TVENPKFRIL TEAEIDAHLV

ALAERD

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9QUM9-1-unknown	MSRGSS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9QUM9-29-unknown	FKAINQ...	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29401
Q9QUM9-30-unknown	KAINQG...	30	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31207
Q9QUM9-78-unknown	CVMTGM...	78	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29402
Q9QUM9-103-unknown	YKYGYE...	103	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34318
Q9QUM9-103-unknown	YKYGYE...	103	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9QUM9-103-unknown	YKYGYE...	103	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9QUM9-105-unknown	YGYEIP...	105	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34319
Q9QUM9-215-unknown	IEVGVV...	215	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34320

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QVEYAF	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29401
...VEYAFK	29	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31207
...TESIGC	77	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29402
...AANWKY	102	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34318
...NWKYKY	104	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34319
...FKPSEI	214	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34320
...LAERD	246	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	28	EYAF.\|.FKAI	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PSA6_MOUSE @28
CATE_MOUSE	29	YAFK.\|.KAIN	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PSA6_MOUSE @29
CATD_MOUSE	77	SIGC.\|.CVMT	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PSA6_MOUSE @77
MMP2_MOUSE	102	NWKY.\|.YKYG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	104	KYKY.\|.YGYE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	214	PSEI.\|.IEVG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)