Q9QUN9: Dickkopf-related protein 3

General Information

Protein names	- Dickkopf-related protein 3 - Dickkopf-3 - Dkk-3 - mDkk-3
Gene names	Dkk3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9QUN9

5 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MQRLGGILLC TLLAAAVPTA PAPSPTVTWT PAEPGPALNY PQEEATLNEM FREVEELMED
        70         80         90        100        110        120
TQHKLRSAVE EMEAEEAAAK TSSEVNLASL PPNYHNETST ETRVGNNTVH VHQEVHKITN
       130        140        150        160        170        180
NQSGQVVFSE TVITSVGDEE GKRSHECIID EDCGPTRYCQ FSSFKYTCQP CRDQQMLCTR
       190        200        210        220        230        240
DSECCGDQLC AWGHCTQKAT KGGNGTICDN QRDCQPGLCC AFQRGLLFPV CTPLPVEGEL
       250        260        270        280        290        300
CHDPTSQLLD LITWELEPEG ALDRCPCASG LLCQPHSHSL VYMCKPAFVG SHDHSEESQL
       310        320        330        340
PREAPDEYED VGFIGEVRQE LEDLERSLAQ EMAFEGPAPV ESLGGEEEI

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9QUN9-23-unknown	PSPTVT...	23	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9QUN9-23-unknown	PSPTVT...	23	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9QUN9-67-unknown	SAVEEM...	67	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34321
Q9QUN9-251-unknown	LITWEL...	251	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34322
Q9QUN9-252-unknown	ITWELE...	252	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34323
Q9QUN9-253-unknown	TWELEP...	253		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QHKLRS	66	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34321
...SQLLDL	250	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34322
...QLLDLI	251	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34323
...GEEEI	349	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	66	KLRS.\|.SAVE	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> DKK3_MOUSE @66
MMP2_MOUSE	250	LLDL.\|.LITW	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	251	LDLI.\|.ITWE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)