Q9QXS1: Plectin
Protein names | - Plectin - PCN - PLTN - Plectin-1 - Plectin-6 |
---|---|
Gene names | Plec |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9QXS1 |
12
N-termini
12
C-termini
6
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
Isoforms
- Isoform PLEC-1 of Plectin - Isoform PLEC-1A of Plectin - Isoform PLEC-1B,2A of Plectin - Isoform PLEC-1B of Plectin - Isoform PLEC-0,1C of Plectin - Isoform PLEC-0,1C,2A of Plectin - Isoform PLEC-0,1C,2A,3A of Plectin - Isoform PLEC-1D,2A of Plectin - Isoform PLEC-1D of Plectin - Isoform PLEC-1E,2A of Plectin - Isoform PLEC-1E of Plectin - Isoform PLEC-1F of Plectin - Isoform PLEC-1G of Plectin - Isoform PLEC-1H of Plectin - Isoform PLEC-1I of PlectinSequence View
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
10 20 30 40 50 60
MVAGMLMPLD RLRAIYEVLF REGVMVAKKD RRPRSLHPHV PGVTNLQVMR AMASLKARGL
70 80 90 100 110 120
VRETFAWCHF YWYLTNEGID HLRQYLHLPP EIVPASLQRV RRPVAMVIPA RRRSPHVQTM
130 140 150 160 170 180
QGPLGCPPKR GPLPAEDPAR EERQVYRRKE REEGAPETPV VSATTVGTLA RPGPEPAPAT
190 200 210 220 230 240
DERDRVQKKT FTKWVNKHLI KHWRAEAQRH ISDLYEDLRD GHNLISLLEV LSGDSLPREK
250 260 270 280 290 300
GRMRFHKLQN VQIALDYLRH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL HFQISDIQVS
310 320 330 340 350 360
GQSEDMTAKE KLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FNAIIHRHKP MLIDMNKVYR
370 380 390 400 410 420
QTNLENLDQA FSVAERDLGV TRLLDPEDVD VPQPDEKSII TYVSSLYDAM PRVPGAQDGV
430 440 450 460 470 480
RANELQLRWQ EYRELVLLLL QWIRHHTAAF EERKFPSSFE EIEILWCQFL KFKETELPAK
490 500 510 520 530 540
EADKNRSKVI YQSLEGAVQA GQLKIPPGYH PLDVEKEWGK LHVAILEREK QLRSEFERLE
550 560 570 580 590 600
CLQRIVSKLQ MEAGLCEEQL NQADALLQSD IRLLASGKVA QRAGEVERDL DKADGMIRLL
610 620 630 640 650 660
FNDVQTLKDG RHPQGEQMYR RVYRLHERLV AIRTEYNLRL KAGVGAPVTQ VTLQSTQRRP
670 680 690 700 710 720
ELEDSTLRYL QDLLAWVEEN QRRIDSAEWG VDLPSVEAQL GSHRGMHQSI EEFRAKIERA
730 740 750 760 770 780
RNDESQLSPA TRGAYRDCLG RLDLQYAKLL NSSKARLRSL ESLHGFVAAA TKELMWLNEK
790 800 810 820 830 840
EEEEVGFDWS DRNTNMAAKK ESYSALMREL EMKEKKIKEI QNTGDRLLRE DHPARPTVES
850 860 870 880 890 900
FQAALQTQWS WMLQLCCCIE AHLKENTAYF QFFSDVREAE EQLQKLQETL RRKYSCDRTI
910 920 930 940 950 960
TVTRLEDLLQ DAQDEKEQLN EYKGHLSGLA KRAKAIVQLK PRNPAHPVRG HVPLIAVCDY
970 980 990 1000 1010 1020
KQVEVTVHKG DQCQLVGPAQ PSHWKVLSGS SSEAAVPSVC FLVPPPNQEA QEAVARLEAQ
1030 1040 1050 1060 1070 1080
HQALVTLWHQ LHVDMKSLLA WQSLSRDIQL IRSWSLVTFR TLKPEEQRQA LRNLELHYQA
1090 1100 1110 1120 1130 1140
FLRDSQDAGG FGPEDRLVAE REYGSCSRHY QQLLQSLEQG EQEESRCQRC ISELKDIRLQ
1150 1160 1170 1180 1190 1200
LEACETRTVH RLRLPLDKDP ARECAQRIAE QQKAQAEVEG LGKGVARLSA EAEKVLALPE
1210 1220 1230 1240 1250 1260
PSPAAPTLRS ELELTLGKLE QVRSLSAIYL EKLKTISLVI RSTQGAEEVL KTHEEQLKEA
1270 1280 1290 1300 1310 1320
QAVPATLQEL EATKASLKKL RAQAEAQQPV FNTLRDELRG AQEVGERLQQ RHGERDVEVE
1330 1340 1350 1360 1370 1380
RWRERVTQLL ERWQAVLAQT DVRQRELEQL GRQLRYYRES ADPLSAWLQD AKRRQEQIQA
1390 1400 1410 1420 1430 1440
VPIANCQAAR EQLRQEKALL EEIERHGEKV EECQKFAKQY INAIKDYELQ LITYKAQLEP
1450 1460 1470 1480 1490 1500
VASPAKKPKV QSGSESVIQE YVDLRTRYSE LTTLTSQYIK FISETLRRME EEERLAEQQR
1510 1520 1530 1540 1550 1560
AEERERLAEV EAALEKQRQL AEAHAQAKAQ AELEAQELQR RMQEEVARRE EAAVDAQQQK
1570 1580 1590 1600 1610 1620
RSIQEELQHL RQSSEAEIQA KAQQVEAAER SRMRIEEEIR VVRLQLETTE RQRGGAEGEL
1630 1640 1650 1660 1670 1680
QALRARAEEA EAQKRQAQEE AERLRRQVQD ESQRKRQAEA ELALRVKAEA EAAREKQRAL
1690 1700 1710 1720 1730 1740
QALDELRLQA EEAERRLRQA EAERARQVQV ALETAQRSAE VELQSKRASF AEKTAQLERT
1750 1760 1770 1780 1790 1800
LQEEHVTVAQ LREEAERRAQ QQAEAERARE EAERELERWQ LKANEALRLR LQAEEVAQQK
1810 1820 1830 1840 1850 1860
SLAQADAEKQ KEEAEREARR RGKAEEQAVR QRELAEQELE KQRQLAEGTA QQRLAAEQEL
1870 1880 1890 1900 1910 1920
IRLRAETEQG EQQRQLLEEE LARLQHEATA ATQKRQELEA ELAKVRAEME VLLASKARAE
1930 1940 1950 1960 1970 1980
EESRSTSEKS KQRLEAEAGR FRELAEEAAR LRALAEEAKR QRQLAEEDAA RQRAEAERVL
1990 2000 2010 2020 2030 2040
TEKLAAISEA TRLKTEAEIA LKEKEAENER LRRLAEDEAF QRRRLEEQAA LHKADIEERL
2050 2060 2070 2080 2090 2100
AQLRKASESE LERQKGLVED TLRQRRQVEE EIMALKVSFE KAAAGKAELE LELGRIRSNA
2110 2120 2130 2140 2150 2160
EDTMRSKEQA ELEAARQRQL AAEEEQRRRE AEERVQRSLA AEEEAARQRK VALEEVERLK
2170 2180 2190 2200 2210 2220
AKVEEARRLR ERAEQESARQ LQLAQEAAQK RLQAEEKAHA FVVQQREEEL QQTLQQEQNM
2230 2240 2250 2260 2270 2280
LDRLRSEAEA ARRAAEEAEE AREQAEREAA QSRKQVEEAE RLKQSAEEQA QAQAQAQAAA
2290 2300 2310 2320 2330 2340
EKLRKEAEQE AARRAQAEQA ALKQKQAADA EMEKHKKFAE QTLRQKAQVE QELTTLRLQL
2350 2360 2370 2380 2390 2400
EETDHQKSIL DEELQRLKAE VTEAARQRSQ VEEELFSVRV QMEELGKLKA RIEAENRALI
2410 2420 2430 2440 2450 2460
LRDKDNTQRF LEEEAEKMKQ VAEEAARLSV AAQEAARLRQ LAEEDLAQQR ALAEKMLKEK
2470 2480 2490 2500 2510 2520
MQAVQEATRL KAEAELLQQQ KELAQEQARR LQEDKEQMAQ QLVEETQGFQ RTLEAERQRQ
2530 2540 2550 2560 2570 2580
LEMSAEAERL KLRMAEMSRA QARAEEDAQR FRKQAEEIGE KLHRTELATQ EKVTLVQTLE
2590 2600 2610 2620 2630 2640
IQRQQSDHDA ERLREAIAEL EREKEKLKQE AKLLQLKSEE MQTVQQEQIL QETQALQKSF
2650 2660 2670 2680 2690 2700
LSEKDSLLQR ERFIEQEKAK LEQLFQDEVA KAKQLREEQQ RQQQQMEQEK QELMASMEEA
2710 2720 2730 2740 2750 2760
RRRQREAEEG VRRKQEELQH LEQQRQQQEK LLAEENQRLR ERLQRLEEEH RAALAHSEIA
2770 2780 2790 2800 2810 2820
TTQAASTKAL PNGRDAPDGP SVEAEPEYTF EGLRQKVPAQ QLQEAGILSQ EELQRLAQGH
2830 2840 2850 2860 2870 2880
TTVAELTQRE DVYRYLKGRS SIAGLLLKPT NEKLSVYTAL QRQLLSPGTA LILLEAQAAS
2890 2900 2910 2920 2930 2940
GFLLDPVRNR RLTVNEAVKE GVVGPELHHK LLSAERAVTG YKDPYTGEQI SLFQAMKKDL
2950 2960 2970 2980 2990 3000
IVRDHGVRLL EAQIATGGII DPVHSHRVPV DVAYKRGYFD EEMNRILSDP SDDTKGFFDP
3010 3020 3030 3040 3050 3060
NTHENLTYLQ LLERCVEDPE TGLRLLPLTD KAAKGGELVY TDTEARDVFE KATVSAPFGK
3070 3080 3090 3100 3110 3120
FQGRTVTIWE IINSEYFTAE QRRDLLQQFR TGHITVEKII KIVITVVEEH ERKGQLCFEG
3130 3140 3150 3160 3170 3180
LRALVPAAEL LDSGVISHEL YQQLQRGERS VREVAEADSV RQALRGTNVI AGVWLEEAGQ
3190 3200 3210 3220 3230 3240
KLSIYEALKK DLLQPEVAVA LLEAQAGTGH IIDPATSARL TVDEAVRAGL VGPELHEKLL
3250 3260 3270 3280 3290 3300
SAEKAVTGYR DPYSGQSVSL FQALKKGLIP REQGLRLLDA QLSTGGIVDP SKSHRVPLDV
3310 3320 3330 3340 3350 3360
AYARGYLDKE TNRALTSPRD DARVYHDPST QEPVTYSQLQ QRCRSDQLTG LSLLPLSEKA
3370 3380 3390 3400 3410 3420
VRARQEEVYS ELQARETLEQ AKVEVPVGSF KGRAMTVWEL ISSEYFTEEQ RQELLRQFRT
3430 3440 3450 3460 3470 3480
GKVTVEKVIK IVITIVEEVE TRRQERLSFS GLRAPVPASE LLDAKILSRA QFDQLKDGKT
3490 3500 3510 3520 3530 3540
SVKELSEVGS VRTLLQGSGC LAGIYLEDSK EKVTIYEAMR RGLLRPSTAT LLLEAQAATG
3550 3560 3570 3580 3590 3600
FLVDPVRNQR LYVHEAVKAG VVGPELHEKL LSAEKAVTGY KDPYSGNTIS LFQAMKKGLV
3610 3620 3630 3640 3650 3660
LRDHAIRLLE AQVATGGIID PVHSHRLPVD VAYQRGYFDE EMNRVLADPS DDTKGFFDPN
3670 3680 3690 3700 3710 3720
THENLTYLQL LERCVEDPET GLRLLPLKGA EKTEVVETTQ VYTEEETRRA FEETQIDIPG
3730 3740 3750 3760 3770 3780
GGSHGGSSMS LWEVMQSNMI PEDQRARLMA DFQAGRVTKE RMIIIIIEII EKTEIIRQQN
3790 3800 3810 3820 3830 3840
LASYDYVRRR LTAEDLYEAR IISLETYNLF REGTKNLREV LEMESAWRYL YGTGAVAGVY
3850 3860 3870 3880 3890 3900
LPGSRQTLTI YQALKKGLLS AEVARLLLEA QAATGFLLDP VKGERLTVDE AVRKGLVGPE
3910 3920 3930 3940 3950 3960
LHDRLLSAER AVTGYRDPYT EQTISLFQAM KKELIPAEEA LRLLDAQLAT GGIVDPRLGF
3970 3980 3990 4000 4010 4020
HLPLEVAYQR GYLNKDTHDQ LSEPSEVRSY VDPSTDERLS YTQLLKRCRR DDPSGQMLLL
4030 4040 4050 4060 4070 4080
LSDARKLTFR GLRKQITVEE LVRSQVMDEA TALQLQEGLT SIEEVTKNLQ KFLEGTSCIA
4090 4100 4110 4120 4130 4140
GVFVDATKER LSVYQAMKKG IIRPGTAFEL LEAQAATGYV IDPIKGLKLT VEEAVRMGIV
4150 4160 4170 4180 4190 4200
GPEFKDKLLS AERAVTGYKD PYSGKLISLF QAMKKGLILK DHGIRLLEAQ IATGGIIDPE
4210 4220 4230 4240 4250 4260
ESHRLPVEVA YKRGLFDEEM NEILTDPSDD TKGFFDPNTE ENLTYLQLME RCITDPQTGL
4270 4280 4290 4300 4310 4320
CLLPLKEKKR ERKTSSKSSV RKRRVVIVDP ETGKEMSVYE AYRKGLIDHQ TYLELSEQEC
4330 4340 4350 4360 4370 4380
EWEEITISSS DGVVKSMIID RRSGRQYDID DAITKNLIDR SALDQYRAGT LSITEFADML
4390 4400 4410 4420 4430 4440
SGNAGGFRSR SSSVGSSSSY PISSAGPRTQ LASWSDPTEE TGPVAGILDT ETLEKVSITE
4450 4460 4470 4480 4490 4500
AMHRNLVDNI TGQRLLEAQA CTGGIIDPST GERFPVTEAV NKGLVDKIMV DRINLAQKAF
4510 4520 4530 4540 4550 4560
CGFEDPRTKT KMSAAQALKK GWLYYEAGQR FLEVQYLTGG LIEPDTPGRV SLDEALQRGT
4570 4580 4590 4600 4610 4620
VDARTAQKLR DVSAYSKYLT CPKTKLKISY KDALDRSMVE EGTGLRLLEA AAQSSKGYYS
4630 4640 4650 4660 4670 4680
PYSVSGSGST AGSRTGSRTG SRAGSRRGSF DATGSGFSMT FSSSSYSSSG YGRRYASGPS
4690
ASLGGPESAV A
Protein Neighborhood
Domains & Features
12 N-termini - 12 C-termini - 6 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9QXS1-1-unknown | MVAGML... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9QXS1-1-unknown | MVAGML... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt85547 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000127261 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000129543 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000126912 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000079668 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt198866 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt198870 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt198872 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt198871 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt198869 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt198868 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt198867 | |||
Q9QXS1-306-unknown | MTAKEK... | 306 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt198873 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31219 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt157998 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158046 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158047 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158062 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158098 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158110 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158119 | |||
Q9QXS1-1553-unknown | AVDAQQ... | 1553 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158246 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31235 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158041 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158093 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158094 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158099 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158137 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158161 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158174 | |||
Q9QXS1-1578-unknown | IQAKAQ... | 1578 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158288 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34329 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158337 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158382 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158383 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158387 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158407 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158409 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158416 | |||
Q9QXS1-1799-unknown | QKSLAQ... | 1799 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158534 | |||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | N-TAILS | Overall CM. | Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... | 20208520 | ||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160801 | ||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160805 | ||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160807 | ||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160806 | ||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160804 | ||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160803 | ||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160802 | ||
Q9QXS1-1896-Pyrrolidone carboxylic acid | QELEAE... | 1896 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160808 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | N-TAILS | Overall CM. | Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... | 20208520 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160817 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160821 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160823 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160822 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160820 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160819 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160818 | ||
Q9QXS1-2054-Pyrrolidone carboxylic acid | QKGLVE... | 2054 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160824 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | N-TAILS | Overall CM. | Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... | 20208520 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160833 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160837 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160839 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160838 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160836 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160835 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160834 | ||
Q9QXS1-2180-Pyrrolidone carboxylic acid | QLQLAQ... | 2180 | pyrrolidone carboxylic acid- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt160840 | ||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34345 | |||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159134 | |||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159150 | |||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159151 | |||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159154 | |||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159168 | |||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159175 | |||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159179 | |||
Q9QXS1-2502-unknown | LVEETQ... | 2502 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159205 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34361 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159277 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159282 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159283 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159285 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159287 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159289 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159292 | |||
Q9QXS1-3130-unknown | LLDSGV... | 3130 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159298 | |||
Q9QXS1-3130-unmodified | LLDSGV... | 3130 | N-TAILS | Overall CM. | Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... | 20208520 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31251 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159301 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159305 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159306 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159310 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159314 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159315 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159316 | |||
Q9QXS1-3352-unknown | SLLPLS... | 3352 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt159318 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LYEDLR | 218 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000130948 | |||
...LYEDLR | 218 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000131946 | |||
...LYEDLR | 218 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt155784 | |||
...LYEDLR | 218 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt155787 | |||
...LYEDLR | 218 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt155785 | |||
...LYEDLR | 218 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt155786 | |||
...LMWLNE | 778 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000130915 | |||
...KESYSA | 804 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000127253 | |||
...KESYSA | 804 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000126912 | |||
...KESYSA | 804 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000127867 | |||
...YKQVEV | 964 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000126936 | |||
...RREEAA | 1552 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31219 | |||
...RREEAA | 1552 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141493 | |||
...RREEAA | 1552 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141541 | |||
...RREEAA | 1552 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141542 | |||
...RREEAA | 1552 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141557 | |||
...RREEAA | 1552 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141593 | |||
...RREEAA | 1552 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141605 | |||
...RREEAA | 1552 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141614 | |||
...RREEAA | 1552 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141742 | |||
...SSEAEI | 1577 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31235 | |||
...SSEAEI | 1577 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141536 | |||
...SSEAEI | 1577 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141588 | |||
...SSEAEI | 1577 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141589 | |||
...SSEAEI | 1577 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141594 | |||
...SSEAEI | 1577 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141632 | |||
...SSEAEI | 1577 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141657 | |||
...SSEAEI | 1577 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141670 | |||
...SSEAEI | 1577 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141784 | |||
...EEVAQQ | 1798 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34329 | |||
...EEVAQQ | 1798 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141834 | |||
...EEVAQQ | 1798 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141879 | |||
...EEVAQQ | 1798 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141880 | |||
...EEVAQQ | 1798 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141884 | |||
...EEVAQQ | 1798 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141904 | |||
...EEVAQQ | 1798 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141906 | |||
...EEVAQQ | 1798 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141914 | |||
...EEVAQQ | 1798 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142038 | |||
...QMAQQL | 2501 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34345 | |||
...QMAQQL | 2501 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142638 | |||
...QMAQQL | 2501 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142654 | |||
...QMAQQL | 2501 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142655 | |||
...QMAQQL | 2501 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142658 | |||
...QMAQQL | 2501 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142672 | |||
...QMAQQL | 2501 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142679 | |||
...QMAQQL | 2501 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142683 | |||
...QMAQQL | 2501 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142709 | |||
...VPAAEL | 3129 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC34361 | |||
...VPAAEL | 3129 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142781 | |||
...VPAAEL | 3129 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142786 | |||
...VPAAEL | 3129 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142787 | |||
...VPAAEL | 3129 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142789 | |||
...VPAAEL | 3129 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142791 | |||
...VPAAEL | 3129 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142793 | |||
...VPAAEL | 3129 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142796 | |||
...VPAAEL | 3129 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142802 | |||
...QLTGLS | 3351 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC31251 | |||
...QLTGLS | 3351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142805 | |||
...QLTGLS | 3351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142809 | |||
...QLTGLS | 3351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142810 | |||
...QLTGLS | 3351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142814 | |||
...QLTGLS | 3351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142818 | |||
...QLTGLS | 3351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142819 | |||
...QLTGLS | 3351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142820 | |||
...QLTGLS | 3351 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142822 | |||
...IIDPVH | 3622 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSMUSP00000130048 | |||
...ESAVA | 4691 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...ESAVA | 4691 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81172 | |||
...ESAVA | 4691 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81166 | |||
...ESAVA | 4691 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81168 | |||
...ESAVA | 4691 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81167 | |||
...ESAVA | 4691 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81169 | |||
...ESAVA | 4691 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81170 | |||
...ESAVA | 4691 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81171 | |||
...ESAVA | 4691 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81165 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 1552 | EEAA.|.AVDA | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> PLEC_MOUSE @1552 | ||
CATE_MOUSE | 1577 | EAEI.|.IQAK | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> PLEC_MOUSE @1577 | ||
MMP2_MOUSE | 1798 | VAQQ.|.QKSL | inferred from experiment | unknown | MEROPS | Merops MMP2_MOUSE -> PLEC_MOUSE @1798 | ||
MMP2_MOUSE | 2501 | AQQL.|.LVEE | inferred from experiment | unknown | MEROPS | Merops MMP2_MOUSE -> PLEC_MOUSE @2501 | ||
MMP2_MOUSE | 3129 | AAEL.|.LLDS | inferred from experiment | unknown | MEROPS | Merops MMP2_MOUSE -> PLEC_MOUSE @3129 | ||
CATE_MOUSE | 3351 | TGLS.|.SLLP | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> PLEC_MOUSE @3351 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|