Q9R1P4: Proteasome subunit alpha type-1

General Information

Protein names	- Proteasome subunit alpha type-1 - 3.4.25.1 {ECO:0000250\|UniProtKB:P25786} - Macropain subunit C2 - Multicatalytic endopeptidase complex subunit C2 - Proteasome component C2 - Proteasome nu chain
Gene names	Psma1
Organism	Mus musculus
Protease Family
Protease ID	T01.976
Chromosome location
UniProt ID	Q9R1P4

6 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MFRNQYDNDV TVWSPQGRIH QIEYAMEAVK QGSATVGLKS KTHAVLVALK RAQSELAAHQ
        70         80         90        100        110        120
KKILHVDNHI GISIAGLTAD ARLLCNFMRQ ECLDSRFVFD RPLPVSRLVS LIGSKTQIPT
       130        140        150        160        170        180
QRYGRRPYGV GLLIAGYDDM GPHIFQTCPS ANYFDCRAMS IGARSQSART YLERHMSEFM
       190        200        210        220        230        240
ECNLDELVKH GLRALRETLP AEQDLTTKNV SIGIVGKDLE FTIYDDDDVS PFLDGLEERP
       250        260
QRKAQPSQAA EEPAEKADEP MEH

Isoforms

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9R1P4-1-Acetylation	MFRNQY...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9R1P4-75-unknown	AGLTAD...	75		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31310
Q9R1P4-108-unknown	LVSLIG...	108		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34387
Q9R1P4-109-unknown	VSLIGS...	109		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31311
Q9R1P4-109-unknown	VSLIGS...	109		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29430
Q9R1P4-183-unmodified	NLDELV...	183			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q9R1P4-232-unknown	FLDGLE...	232		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34388

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IGISIA	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31310
...LPVSRL	107	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34387
...PVSRLV	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31311
...PVSRLV	108	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29430
...DDVSPF	231	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34388
...EPMEH	263	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	74	ISIA.\|.AGLT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PSA1_MOUSE @74
MMP2_MOUSE	107	VSRL.\|.LVSL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	108	SRLV.\|.VSLI	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PSA1_MOUSE @108
CATD_MOUSE	108	SRLV.\|.VSLI	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> PSA1_MOUSE @108
MMP2_MOUSE	231	VSPF.\|.FLDG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)