TopFIND 4.0

Q9UDY8: Mucosa-associated lymphoid tissue lymphoma translocation protein 1

General Information

Protein names
- Mucosa-associated lymphoid tissue lymphoma translocation protein 1
- 3.4.22.-
- MALT lymphoma-associated translocation
- Paracaspase
Gene names MALT1
Organism Homo sapiens
Protease Family C14.026
Protease ID C14.026
Chromosome location
UniProt ID Q9UDY8

3

N-termini

1

C-termini

0

Cleavages

6

Substrates

Sequence

        10         20         30         40         50         60 
MSLLGDPLQA LPPSAAPTGP LLAPPAGATL NRLREPLLRR LSELLDQAPE GRGWRRLAEL 
        70         80         90        100        110        120 
AGSRGRLRLS CLDLEQCSLK VLEPEGSPSL CLLKLMGEKG CTVTELSDFL QAMEHTEVLQ 
       130        140        150        160        170        180 
LLSPPGIKIT VNPESKAVLA GQFVKLCCRA TGHPFVQYQW FKMNKEIPNG NTSELIFNAV 
       190        200        210        220        230        240 
HVKDAGFYVC RVNNNFTFEF SQWSQLDVCD IPESFQRSVD GVSESKLQIC VEPTSQKLMP 
       250        260        270        280        290        300 
GSTLVLQCVA VGSPIPHYQW FKNELPLTHE TKKLYMVPYV DLEHQGTYWC HVYNDRDSQD 
       310        320        330        340        350        360 
SKKVEIIIGR TDEAVECTED ELNNLGHPDN KEQTTDQPLA KDKVALLIGN MNYREHPKLK 
       370        380        390        400        410        420 
APLVDVYELT NLLRQLDFKV VSLLDLTEYE MRNAVDEFLL LLDKGVYGLL YYAGHGYENF 
       430        440        450        460        470        480 
GNSFMVPVDA PNPYRSENCL CVQNILKLMQ EKETGLNVFL LDMCRKRNDY DDTIPILDAL 
       490        500        510        520        530        540 
KVTANIVFGY ATCQGAEAFE IQHSGLANGI FMKFLKDRLL EDKKITVLLD EVAEDMGKCH 
       550        560        570        580        590        600 
LTKGKQALEI RSSLSEKRAL TDPIQGTEYS AESLVRNLQW AKAHELPESM CLKFDCGVQI 
       610        620        630        640        650        660 
QLGFAAEFSN VMIIYTSIVY KPPEIIMCDA YVTDFPLDLD IDPKDANKGT PEETGSYLVS 
       670        680        690        700        710        720 
KDLPKHCLYT RLSSLQKLKE HLVFTVCLSY QYSGLEDTVE DKQEVNVGKP LIAKLDMHRG 
       730        740        750        760        770        780 
LGRKTCFQTC LMSNGPYQSS AATSGGAGHY HSLQDPFHGV YHSHPGNPSN VTPADSCHCS 
       790        800        810        820    
RTPDAFISSF AHHASCHFSR SNVPVETTDE IPFSFSDRLR ISEK

Isoforms

- Isoform 2 of Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Sequence View

        10         20         30         40         50         60 
MSLLGDPLQA LPPSAAPTGP LLAPPAGATL NRLREPLLRR LSELLDQAPE GRGWRRLAEL 
        70         80         90        100        110        120 
AGSRGRLRLS CLDLEQCSLK VLEPEGSPSL CLLKLMGEKG CTVTELSDFL QAMEHTEVLQ 
       130        140        150        160        170        180 
LLSPPGIKIT VNPESKAVLA GQFVKLCCRA TGHPFVQYQW FKMNKEIPNG NTSELIFNAV 
       190        200        210        220        230        240 
HVKDAGFYVC RVNNNFTFEF SQWSQLDVCD IPESFQRSVD GVSESKLQIC VEPTSQKLMP 
       250        260        270        280        290        300 
GSTLVLQCVA VGSPIPHYQW FKNELPLTHE TKKLYMVPYV DLEHQGTYWC HVYNDRDSQD 
       310        320        330        340        350        360 
SKKVEIIIGR TDEAVECTED ELNNLGHPDN KEQTTDQPLA KDKVALLIGN MNYREHPKLK 
       370        380        390        400        410        420 
APLVDVYELT NLLRQLDFKV VSLLDLTEYE MRNAVDEFLL LLDKGVYGLL YYAGHGYENF 
       430        440        450        460        470        480 
GNSFMVPVDA PNPYRSENCL CVQNILKLMQ EKETGLNVFL LDMCRKRNDY DDTIPILDAL 
       490        500        510        520        530        540 
KVTANIVFGY ATCQGAEAFE IQHSGLANGI FMKFLKDRLL EDKKITVLLD EVAEDMGKCH 
       550        560        570        580        590        600 
LTKGKQALEI RSSLSEKRAL TDPIQGTEYS AESLVRNLQW AKAHELPESM CLKFDCGVQI 
       610        620        630        640        650        660 
QLGFAAEFSN VMIIYTSIVY KPPEIIMCDA YVTDFPLDLD IDPKDANKGT PEETGSYLVS 
       670        680        690        700        710        720 
KDLPKHCLYT RLSSLQKLKE HLVFTVCLSY QYSGLEDTVE DKQEVNVGKP LIAKLDMHRG 
       730        740        750        760        770        780 
LGRKTCFQTC LMSNGPYQSS AATSGGAGHY HSLQDPFHGV YHSHPGNPSN VTPADSCHCS 
       790        800        810        820    
RTPDAFISSF AHHASCHFSR SNVPVETTDE IPFSFSDRLR ISEK



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 6 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RISEK 824 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RISEK 824 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt75963

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates