TopFIND 4.0

Q9UHI8: A disintegrin and metalloproteinase with thrombospondin motifs 1

General Information

Protein names
- A disintegrin and metalloproteinase with thrombospondin motifs 1
- ADAM-TS 1
- ADAM-TS1
- ADAMTS-1
- 3.4.24.-
- METH-1
Gene names ADAMTS1
Organism Homo sapiens
Protease Family M12.222
Protease ID M12.222
Chromosome location
UniProt ID Q9UHI8

4

N-termini

5

C-termini

6

Cleavages

26

Substrates

Sequence

        10         20         30         40         50         60 
MQRAVPEGFG RRKLGSDMGN AERAPGSRSF GPVPTLLLLA AALLAVSDAL GRPSEEDEEL 
        70         80         90        100        110        120 
VVPELERAPG HGTTRLRLHA FDQQLDLELR PDSSFLAPGF TLQNVGRKSG SETPLPETDL 
       130        140        150        160        170        180 
AHCFYSGTVN GDPSSAAALS LCEGVRGAFY LLGEAYFIQP LPAASERLAT AAPGEKPPAP 
       190        200        210        220        230        240 
LQFHLLRRNR QGDVGGTCGV VDDEPRPTGK AETEDEDEGT EGEDEGAQWS PQDPALQGVG 
       250        260        270        280        290        300 
QPTGTGSIRK KRFVSSHRYV ETMLVADQSM AEFHGSGLKH YLLTLFSVAA RLYKHPSIRN 
       310        320        330        340        350        360 
SVSLVVVKIL VIHDEQKGPE VTSNAALTLR NFCNWQKQHN PPSDRDAEHY DTAILFTRQD 
       370        380        390        400        410        420 
LCGSQTCDTL GMADVGTVCD PSRSCSVIED DGLQAAFTTA HELGHVFNMP HDDAKQCASL 
       430        440        450        460        470        480 
NGVNQDSHMM ASMLSNLDHS QPWSPCSAYM ITSFLDNGHG ECLMDKPQNP IQLPGDLPGT 
       490        500        510        520        530        540 
SYDANRQCQF TFGEDSKHCP DAASTCSTLW CTGTSGGVLV CQTKHFPWAD GTSCGEGKWC 
       550        560        570        580        590        600 
INGKCVNKTD RKHFDTPFHG SWGMWGPWGD CSRTCGGGVQ YTMRECDNPV PKNGGKYCEG 
       610        620        630        640        650        660 
KRVRYRSCNL EDCPDNNGKT FREEQCEAHN EFSKASFGSG PAVEWIPKYA GVSPKDRCKL 
       670        680        690        700        710        720 
ICQAKGIGYF FVLQPKVVDG TPCSPDSTSV CVQGQCVKAG CDRIIDSKKK FDKCGVCGGN 
       730        740        750        760        770        780 
GSTCKKISGS VTSAKPGYHD IITIPTGATN IEVKQRNQRG SRNNGSFLAI KAADGTYILN 
       790        800        810        820        830        840 
GDYTLSTLEQ DIMYKGVVLR YSGSSAALER IRSFSPLKEP LTIQVLTVGN ALRPKIKYTY 
       850        860        870        880        890        900 
FVKKKKESFN AIPTFSAWVI EEWGECSKSC ELGWQRRLVE CRDINGQPAS ECAKEVKPAS 
       910        920        930        940        950        960 
TRPCADHPCP QWQLGEWSSC SKTCGKGYKK RSLKCLSHDG GVLSHESCDP LKKPKHFIDF 
   
CTMAECS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 6 Cleavages - 26 Substrates

N-termini

C-termini

Cleavages

Substrates