TopFIND 4.0

Q9ULZ9: Matrix metalloproteinase-17

General Information

Protein names
- Matrix metalloproteinase-17
- MMP-17
- 3.4.24.-
- Membrane-type matrix metalloproteinase 4
- MT-MMP 4
- MTMMP4
- Membrane-type-4 matrix metalloproteinase
- MT4-MMP
- MT4MMP
Gene names MMP17
Organism Homo sapiens
Protease Family M10.017
Protease ID M10.017
Chromosome location
UniProt ID Q9ULZ9

3

N-termini

2

C-termini

0

Cleavages

25

Substrates

Sequence

        10         20         30         40         50         60 
MRRRAARGPG PPPPGPGLSR LPLPLLLLLA LGTRGGCAAP APAPRAEDLS LGVEWLSRFG 
        70         80         90        100        110        120 
YLPPADPTTG QLQTQEELSK AITAMQQFGG LEATGILDEA TLALMKTPRC SLPDLPVLTQ 
       130        140        150        160        170        180 
ARRRRQAPAP TKWNKRNLSW RVRTFPRDSP LGHDTVRALM YYALKVWSDI APLNFHEVAG 
       190        200        210        220        230        240 
SAADIQIDFS KADHNDGYPF DGPGGTVAHA FFPGHHHTAG DTHFDDDEAW TFRSSDAHGM 
       250        260        270        280        290        300 
DLFAVAVHEF GHAIGLSHVA AAHSIMRPYY QGPVGDPLRY GLPYEDKVRV WQLYGVRESV 
       310        320        330        340        350        360 
SPTAQPEEPP LLPEPPDNRS SAPPRKDVPH RCSTHFDAVA QIRGEAFFFK GKYFWRLTRD 
       370        380        390        400        410        420 
RHLVSLQPAQ MHRFWRGLPL HLDSVDAVYE RTSDHKIVFF KGDRYWVFKD NNVEEGYPRP 
       430        440        450        460        470        480 
VSDFSLPPGG IDAAFSWAHN DRTYFFKDQL YWRYDDHTRH MDPGYPAQSP LWRGVPSTLD 
       490        500        510        520        530        540 
DAMRWSDGAS YFFRGQEYWK VLDGELEVAP GYPQSTARDW LVCGDSQADG SVAAGVDAAE 
       550        560        570        580        590        600 
GPRAPPGQHD QSRSEDGYEV CSCTSGASSP PGAPGPLVAA TMLLLLPPLS PGALWTAAQA 
   
LTL

Isoforms

- Isoform Short of Matrix metalloproteinase-17

Sequence View

        10         20         30         40         50         60 
MRRRAARGPG PPPPGPGLSR LPLPLLLLLA LGTRGGCAAP APAPRAEDLS LGVEWLSRFG 
        70         80         90        100        110        120 
YLPPADPTTG QLQTQEELSK AITAMQQFGG LEATGILDEA TLALMKTPRC SLPDLPVLTQ 
       130        140        150        160        170        180 
ARRRRQAPAP TKWNKRNLSW RVRTFPRDSP LGHDTVRALM YYALKVWSDI APLNFHEVAG 
       190        200        210        220        230        240 
SAADIQIDFS KADHNDGYPF DGPGGTVAHA FFPGHHHTAG DTHFDDDEAW TFRSSDAHGM 
       250        260        270        280        290        300 
DLFAVAVHEF GHAIGLSHVA AAHSIMRPYY QGPVGDPLRY GLPYEDKVRV WQLYGVRESV 
       310        320        330        340        350        360 
SPTAQPEEPP LLPEPPDNRS SAPPRKDVPH RCSTHFDAVA QIRGEAFFFK GKYFWRLTRD 
       370        380        390        400        410        420 
RHLVSLQPAQ MHRFWRGLPL HLDSVDAVYE RTSDHKIVFF KGDRYWVFKD NNVEEGYPRP 
       430        440        450        460        470        480 
VSDFSLPPGG IDAAFSWAHN DRTYFFKDQL YWRYDDHTRH MDPGYPAQSP LWRGVPSTLD 
       490        500        510        520        530        540 
DAMRWSDGAS YFFRGQEYWK VLDGELEVAP GYPQSTARDW LVCGDSQADG SVAAGVDAAE 
       550        560        570        580        590        600 
GPRAPPGQHD QSRSEDGYEV CSCTSGASSP PGAPGPLVAA TMLLLLPPLS PGALWTAAQA 
   
LTL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 25 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates