Q9UM22: Mammalian ependymin-related protein 1

General Information

Protein names	- Mammalian ependymin-related protein 1 - MERP-1 {ECO:0000303\|PubMed:11749721} - Upregulated in colorectal cancer gene 1 protein
Gene names	EPDR1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UM22

6 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Mammalian ependymin-related protein 1 - Isoform 3 of Mammalian ependymin-related protein 1

Sequence View

        10         20         30         40         50         60
MPGRAPLRTV PGALGAWLLG GLWAWTLCGL CSLGAVGAPR PCQAPQQWEG RQVMYQQSSG
        70         80         90        100        110        120
RNSRALLSYD GLNQRVRVLD ERKALIPCKR LFEYILLYKD GVMFQIDQAT KQCSKMTLTQ
       130        140        150        160        170        180
PWDPLDIPQN STFEDQYSIG GPQEQITVQE WSDRKSARSY ETWIGIYTVK DCYPVQETFT
       190        200        210        220
INYSVILSTR FFDIQLGIKD PSVFTPPSTC QMAQLEKMSE DCSW         10         20         30         40         50         60
MPGRAPLRTV PGALGAWLLG GLWAWTLCGL CSLGAVGAPR PCQAPQQWEG RQVMYQQSSG
        70         80         90        100        110        120
RNSRALLSYD GLNQRVRVLD ERKALIPCKR LFEYILLYKD GVMFQIDQAT KQCSKMTLTQ
       130        140        150        160        170        180
PWDPLDIPQN STFEDQYSIG GPQEQITVQE WSDRKSARSY ETWIGIYTVK DCYPVQETFT
       190        200        210        220
INYSVILSTR FFDIQLGIKD PSVFTPPSTC QMAQLEKMSE DCSW

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UM22-1-unknown	MPGRAP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74013
Q9UM22-34-	GAVGAP...	34		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UM22-34-	GAVGAP...	34		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9UM22-34-unknown	GAVGAP...	34	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt174122
Q9UM22-37-	GAPRPC...	37		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9UM22-37-unknown	GAPRPC...	37	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169298
Q9UM22-38-unknown	APRPCQ...	38	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UM22-38-unknown	APRPCQ...	38		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9UM22-38-unknown	APRPCQ...	38	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt115347

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IPCKRL	90	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69631
...EDCSW	224	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EDCSW	224	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt69632

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)