Q9UMS0: NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

General Information

Protein names	- NFU1 iron-sulfur cluster scaffold homolog, mitochondrial - HIRA-interacting protein 5 {ECO:0000303\|PubMed:11342215}
Gene names	NFU1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UMS0

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of NFU1 iron-sulfur cluster scaffold homolog, mitochondrial - Isoform 3 of NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

Sequence View

        10         20         30         40         50         60
MAATARRGWG AAAVAAGLRR RFCHMLKNPY TIKKQPLHQF VQRPLFPLPA AFYHPVRYMF
        70         80         90        100        110        120
IQTQDTPNPN SLKFIPGKPV LETRTMDFPT PAAAFRSPLA RQLFRIEGVK SVFFGPDFIT
       130        140        150        160        170        180
VTKENEELDW NLLKPDIYAT IMDFFASGLP LVTEETPSGE AGSEEDDEVV AMIKELLDTR
       190        200        210        220        230        240
IRPTVQEDGG DVIYKGFEDG IVQLKLQGSC TSCPSSIITL KNGIQNMLQF YIPEVEGVEQ
       250
VMDDESDEKE ANSP         10         20         30         40         50         60
MAATARRGWG AAAVAAGLRR RFCHMLKNPY TIKKQPLHQF VQRPLFPLPA AFYHPVRYMF
        70         80         90        100        110        120
IQTQDTPNPN SLKFIPGKPV LETRTMDFPT PAAAFRSPLA RQLFRIEGVK SVFFGPDFIT
       130        140        150        160        170        180
VTKENEELDW NLLKPDIYAT IMDFFASGLP LVTEETPSGE AGSEEDDEVV AMIKELLDTR
       190        200        210        220        230        240
IRPTVQEDGG DVIYKGFEDG IVQLKLQGSC TSCPSSIITL KNGIQNMLQF YIPEVEGVEQ
       250
VMDDESDEKE ANSP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UMS0-1-unknown	MAATAR...	1		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9UMS0-1-unknown	MAATAR...	1		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9UMS0-10-unknown	GAAAVA...	10	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UMS0-25-unknown	MLKNPY...	25	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82793
Q9UMS0-59-unknown	MFIQTQ...	59	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164348
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9UMS0-59-	MFIQTQ...	59		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9UMS0-142-unknown	MDFFAS...	142	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82792
Q9UMS0-142-unknown	MDFFAS...	142	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt101810

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EANSP	254	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EANSP	254	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt78410
...EANSP	254	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt78411

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)