Q9Y6G9: Cytoplasmic dynein 1 light intermediate chain 1

General Information

Protein names	- Cytoplasmic dynein 1 light intermediate chain 1 - LIC1 - Dynein light chain A - DLC-A - Dynein light intermediate chain 1, cytosolic
Gene names	DYNC1LI1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y6G9

5 N-termini

5 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAVGRVGSF GSSPPGLSST YTGGPLGNEI ASGNGGAAAG DDEDGQNLWS CILSEVSTRS
        70         80         90        100        110        120
RSKLPAGKNV LLLGEDGAGK TSLIRKIQGI EEYKKGRGLE YLYLNVHDED RDDQTRCNVW
       130        140        150        160        170        180
ILDGDLYHKG LLKFSLDAVS LKDTLVMLVV DMSKPWTALD SLQKWASVVR EHVDKLKIPP
       190        200        210        220        230        240
EEMKQMEQKL IRDFQEYVEP GEDFPASPQR RNTASQEDKD DSVVLPLGAD TLTHNLGIPV
       250        260        270        280        290        300
LVVCTKCDAI SVLEKEHDYR DEHFDFIQSH IRKFCLQYGA ALIYTSVKEN KNIDLVYKYI
       310        320        330        340        350        360
VQKLYGFPYK IPAVVVEKDA VFIPAGWDND KKIGILHENF QTLKAEDNFE DIITKPPVRK
       370        380        390        400        410        420
FVHEKEIMAE DDQVFLMKLQ SLLAKQPPTA AGRPVDASPR VPGGSPRTPN RSVSSNVASV
       430        440        450        460        470        480
SPIPAGSKKI DPNMKAGATS EGVLANFFNS LLSKKTGSPG GPGVSGGSPA GGAGGGSSGL
       490        500        510        520
PPSTKKSGQK PVLDVHAELD RITRKPVTVS PTTPTSPTEG EAS

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y6G9-1-unknown	MAAVGR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y6G9-320-	AVFIPA...	320		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9Y6G9-351-unknown	DIITKP...	351	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19889
Q9Y6G9-417-	VASVSP...	417		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q9Y6G9-419-	SVSPIP...	419		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...MLVVDM	151	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000409019
...GIPVLV	241	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000390507
...EDNFED	350	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19889
...EGEAS	523		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EGEAS	523		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...EGEAS	523	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EGEAS	523		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...EGEAS	523		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	350	NFED.\|.DIIT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)