Q9Z1Q5: Chloride intracellular channel protein 1

General Information

Protein names	- Chloride intracellular channel protein 1 - Nuclear chloride ion channel 27 - NCC27
Gene names	Clic1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Z1Q5

10 N-termini

7 C-termini

8 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAEEQPQVEL FVKAGSDGAK IGNCPFSQRL FMVLWLKGVT FNVTTVDTKR RTETVQKLCP
        70         80         90        100        110        120
GGQLPFLLYG TEVHTDTNKI EEFLEAMLCP PRYPKLAALN PESNTSGLDI FAKFSAYIKN
       130        140        150        160        170        180
SNPALNDNLE KGLLKALKVL DNYLTSPLPE EVDETSAEDE GISQRKFLDG NELTLADCNL
       190        200        210        220        230        240
LPKLHIVQVV CKKYRGFTIP EAFRGVHRYL SNAYAREEFA STCPDDEEIE LAYEQVARAL

K

Isoforms

Sequence View

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Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

10 N-termini - 7 C-termini - 8 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Z1Q5-2-unknown	MAEEQP...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9Z1Q5-2-unknown	MAEEQP...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Z1Q5-2-Acetylation	AEEQPQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Z1Q5-2-Acetylation	AEEQPQ...	2	acetylation-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
Q9Z1Q5-2-Acetylation	AEEQPQ...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9Z1Q5-10-unknown	LFVKAG...	10		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31371
Q9Z1Q5-11-unknown	FVKAGS...	11		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29449
Q9Z1Q5-11-unknown	FVKAGS...	11		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31372
Q9Z1Q5-12-unknown	VKAGSD...	12		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29450
Q9Z1Q5-12-unknown	VKAGSD...	12		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31373
Q9Z1Q5-14-unmodified	AGSDGA...	14			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q9Z1Q5-209-unmodified	YLSNAY...	209			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q9Z1Q5-220-unknown	ASTCPD...	220		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31374
Q9Z1Q5-229-unknown	IELAYE...	229		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31375
Q9Z1Q5-231-unknown	LAYEQV...	231		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31376

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QPQVEL	9	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31371
...PQVELF	10	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29449
...PQVELF	10	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31372
...QVELFV	11	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29450
...QVELFV	11	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31373
...AREEFA	219	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31374
...PDDEEI	228	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31375
...DEEIEL	230	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31376
...ARALK	241	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	9	QVEL.\|.LFVK	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> CLIC1_MOUSE @9
CATD_MOUSE	10	VELF.\|.FVKA	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> CLIC1_MOUSE @10
CATE_MOUSE	10	VELF.\|.FVKA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> CLIC1_MOUSE @10
CATD_MOUSE	11	ELFV.\|.VKAG	inferred from experiment	unknown	MEROPS	Merops CATD_MOUSE -> CLIC1_MOUSE @11
CATE_MOUSE	11	ELFV.\|.VKAG	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> CLIC1_MOUSE @11
CATE_MOUSE	219	EEFA.\|.ASTC	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> CLIC1_MOUSE @219
CATE_MOUSE	228	DEEI.\|.IELA	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> CLIC1_MOUSE @228
CATE_MOUSE	230	EIEL.\|.LAYE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> CLIC1_MOUSE @230

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)