TopFIND 4.0

O15072: A disintegrin and metalloproteinase with thrombospondin motifs 3

General Information

Protein names
- A disintegrin and metalloproteinase with thrombospondin motifs 3
- ADAM-TS 3
- ADAM-TS3
- ADAMTS-3
- 3.4.24.-
- Procollagen II N-proteinase
- PC II-NP
- Procollagen II amino propeptide-processing enzyme
Gene names ADAMTS3
Organism Homo sapiens
Protease Family
Protease ID M12.220
Chromosome location
UniProt ID O15072

3

N-termini

3

C-termini

6

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVLLSLWLIA AALVEVRTSA DGQAGNEEMV QIDLPIKRYR EYELVTPVST NLEGRYLSHT 
        70         80         90        100        110        120 
LSASHKKRSA RDVSSNPEQL FFNITAFGKD FHLRLKPNTQ LVAPGAVVEW HETSLVPGNI 
       130        140        150        160        170        180 
TDPINNHQPG SATYRIRRTE PLQTNCAYVG DIVDIPGTSV AISNCDGLAG MIKSDNEEYF 
       190        200        210        220        230        240 
IEPLERGKQM EEEKGRIHVV YKRSAVEQAP IDMSKDFHYR ESDLEGLDDL GTVYGNIHQQ 
       250        260        270        280        290        300 
LNETMRRRRH AGENDYNIEV LLGVDDSVVR FHGKEHVQNY LLTLMNIVNE IYHDESLGVH 
       310        320        330        340        350        360 
INVVLVRMIM LGYAKSISLI ERGNPSRSLE NVCRWASQQQ RSDLNHSEHH DHAIFLTRQD 
       370        380        390        400        410        420 
FGPAGMQGYA PVTGMCHPVR SCTLNHEDGF SSAFVVAHET GHVLGMEHDG QGNRCGDETA 
       430        440        450        460        470        480 
MGSVMAPLVQ AAFHRYHWSR CSGQELKRYI HSYDCLLDDP FDHDWPKLPE LPGINYSMDE 
       490        500        510        520        530        540 
QCRFDFGVGY KMCTAFRTFD PCKQLWCSHP DNPYFCKTKK GPPLDGTECA AGKWCYKGHC 
       550        560        570        580        590        600 
MWKNANQQKQ DGNWGSWTKF GSCSRTCGTG VRFRTRQCNN PMPINGGQDC PGVNFEYQLC 
       610        620        630        640        650        660 
NTEECQKHFE DFRAQQCQQR NSHFEYQNTK HHWLPYEHPD PKKRCHLYCQ SKETGDVAYM 
       670        680        690        700        710        720 
KQLVHDGTHC SYKDPYSICV RGECVKVGCD KEIGSNKVED KCGVCGGDNS HCRTVKGTFT 
       730        740        750        760        770        780 
RTPRKLGYLK MFDIPPGARH VLIQEDEASP HILAIKNQAT GHYILNGKGE EAKSRTFIDL 
       790        800        810        820        830        840 
GVEWDYNIED DIESLHTDGP LHDPVIVLII PQENDTRSSL TYKYIIHEDS VPTINSNNVI 
       850        860        870        880        890        900 
QEELDTFEWA LKSWSQCSKP CGGGFQYTKY GCRRKSDNKM VHRSFCEANK KPKPIRRMCN 
       910        920        930        940        950        960 
IQECTHPLWV AEEWEHCTKT CGSSGYQLRT VRCLQPLLDG TNRSVHSKYC MGDRPESRRP 
       970        980        990       1000       1010       1020 
CNRVPCPAQW KTGPWSECSV TCGEGTEVRQ VLCRAGDHCD GEKPESVRAC QLPPCNDEPC 
      1030       1040       1050       1060       1070       1080 
LGDKSIFCQM EVLARYCSIP GYNKLCCESC SKRSSTLPPP YLLEAAETHD DVISNPSDLP 
      1090       1100       1110       1120       1130       1140 
RSLVMPTSLV PYHSETPAKK MSLSSISSVG GPNAYAAFRP NSKPDGANLR QRSAQQAGSK 
      1150       1160       1170       1180       1190       1200 
TVRLVTVPSS PPTKRVHLSS ASQMAAASFF AASDSIGASS QARTSKKDGK IIDNRRPTRS 
   
STLER

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 6 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)