O43396: Thioredoxin-like protein 1

General Information

Protein names	- Thioredoxin-like protein 1 - 32 kDa thioredoxin-related protein
Gene names	TXNL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O43396

7 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MVGVKPVGSD PDFQPELSGA GSRLAVVKFT MRGCGPCLRI APAFSSMSNK YPQAVFLEVD
        70         80         90        100        110        120
VHQCQGTAAT NNISATPTFL FFRNKVRIDQ YQGADAVGLE EKIKQHLEND PGSNEDTDIP
       130        140        150        160        170        180
KGYMDLMPFI NKAGCECLNE SDEHGFDNCL RKDTTFLESD CDEQLLITVA FNQPVKLYSM
       190        200        210        220        230        240
KFQGPDNGQG PKYVKIFINL PRSMDFEEAE RSEPTQALEL TEDDIKEDGI VPLRYVKFQN
       250        260        270        280
VNSVTIFVQS NQGEEETTRI SYFTFIGTPV QATNMNDFKR VVGKKGESH

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
O43396-1-	MVGVKP...	1			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O43396-1-unknown	MVGVKP...	1			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O43396-1-unknown	MVGVKP...	1			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O43396-2-	VGVKPV...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
O43396-2-	VGVKPV...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O43396-2-	VGVKPV...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O43396-2-	VGVKPV...	2			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
O43396-2-	VGVKPV...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O43396-2-	VGVKPV...	2			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
O43396-2-	VGVKPV...	2			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O43396-2-acetylation	VGVKPV...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O43396-2-unknown	VGVKPV...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O43396-2-unknown	VGVKPV...	2			COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
O43396-2-unknown	VGVKPV...	2			COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
O43396-3-	GVKPVG...	3			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O43396-3-	GVKPVG...	3			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O43396-3-	GVKPVG...	3			N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
O43396-124-unknown	MDLMPF...	124		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000440251

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...RLAVVK	27	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000465606
...DNCLRK	151	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000466558
...KGESH	289	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KGESH	289		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)