O70310: Glycylpeptide N-tetradecanoyltransferase 1

General Information

Protein names	- Glycylpeptide N-tetradecanoyltransferase 1 - 2.3.1.97 {ECO:0000269\|PubMed:15753093} - Myristoyl-CoA:protein N-myristoyltransferase 1 - NMT 1 - Type I N-myristoyltransferase - Peptide N-myristoyltransferase 1
Gene names	Nmt1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	O70310

9 N-termini

4 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADESETAVK LPAPSLPLMM EGNGNGHEHC SDCENEEDNS HNRSGLSPAN DTGAKKKKKK
        70         80         90        100        110        120
QKKKKEKGSD MESTQDQPVK MTSLPAERIQ EIQKAIELFS VGQGPAKTME EASKRSYQFW
       130        140        150        160        170        180
DTQPVPKLGE VVNTHGPVEP DKDNIRQEPY TLPQGFTWDA LDLGDRGVLK ELYTLLNENY
       190        200        210        220        230        240
VEDDDNMFRF DYSPEFLLWA LRPPGWLPQW HCGVRVVSSR KLVGFISAIP ANIHIYDTEK
       250        260        270        280        290        300
KMVEINFLCV HKKLRSKRVA PVLIREITRR VHLEGIFQAV YTAGVVLPKP VGTCRYWHRS
       310        320        330        340        350        360
LNPRKLIEVK FSHLSRNMTM QRTMKLYRLP ETPKTAGLRP MEKKDIPVVH QLLSRYLKQF
       370        380        390        400        410        420
HLTPVMNQEE VEHWFYPQEN IIDTFVVENA NGEVTDFLSF YTLPSTIMNH PTHKSLKAAY
       430        440        450        460        470        480
SFYNVHTQTP LLDLMSDALV LAKMKGFDVF NALDLMENKT FLEKLKFGIG DGNLQYYLYN
       490
WKCPSMGAEK VGLVLQ

Isoforms

Sequence View

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Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O70310-1-unknown	MADESE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O70310-14-unknown	PSLPLM...	14		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
O70310-99-unknown	FSVGQG...	99		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29558
O70310-99-unknown	FSVGQG...	99		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28667
O70310-100-unknown	SVGQGP...	100		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29559
O70310-100-unknown	SVGQGP...	100		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28668
O70310-128-unknown	LGEVVN...	128			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
O70310-131-acetylation	VVNTHG...	131	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
O70310-132-unmodified	VNTHGP...	132			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
O70310-155-unmodified	GFTWDA...	155			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
O70310-156-unknown	FTWDAL...	156		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33161

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KAIELF	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29558
...KAIELF	98	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28667
...AIELFS	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29559
...AIELFS	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28668
...TLPQGF	155	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33161
...GLVLQ	496	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	98	IELF.\|.FSVG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> NMT1_MOUSE @98
CATD_MOUSE	98	IELF.\|.FSVG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> NMT1_MOUSE @98
CATE_MOUSE	99	ELFS.\|.SVGQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> NMT1_MOUSE @99
CATD_MOUSE	99	ELFS.\|.SVGQ	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> NMT1_MOUSE @99
MMP2_MOUSE	155	PQGF.\|.FTWD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)