P02468: Laminin subunit gamma-1
| Protein names | - Laminin subunit gamma-1 - Laminin B2 chain - Laminin-1 subunit gamma - Laminin-10 subunit gamma - Laminin-11 subunit gamma - Laminin-2 subunit gamma - Laminin-3 subunit gamma - Laminin-4 subunit gamma - Laminin-6 subunit gamma - Laminin-7 subunit gamma - Laminin-8 subunit gamma - Laminin-9 subunit gamma - S-laminin subunit gamma - S-LAM gamma |
|---|---|
| Gene names | Lamc1 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P02468 |
7
N-termini
5
C-termini
4
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MTGGGRAALA LQPRGRLWPL LAVLAAVAGC VRAAMDECAD EGGRPQRCMP EFVNAAFNVT
70 80 90 100 110 120
VVATNTCGTP PEEYCVQTGV TGVTKSCHLC DAGQQHLQHG AAFLTDYNNQ ADTTWWQSQT
130 140 150 160 170 180
MLAGVQYPNS INLTLHLGKA FDITYVRLKF HTSRPESFAI YKRTREDGPW IPYQYYSGSC
190 200 210 220 230 240
ENTYSKANRG FIRTGGDEQQ ALCTDEFSDI SPLTGGNVAF STLEGRPSAY NFDNSPVLQE
250 260 270 280 290 300
WVTATDIRVT LNRLNTFGDE VFNEPKVLKS YYYAISDFAV GGRCKCNGHA SECVKNEFDK
310 320 330 340 350 360
LMCNCKHNTY GVDCEKCLPF FNDRPWRRAT AESASESLPC DCNGRSQECY FDPELYRSTG
370 380 390 400 410 420
HGGHCTNCRD NTDGAKCERC RENFFRLGNT EACSPCHCSP VGSLSTQCDS YGRCSCKPGV
430 440 450 460 470 480
MGDKCDRCQP GFHSLTEAGC RPCSCDLRGS TDECNVETGR CVCKDNVEGF NCERCKPGFF
490 500 510 520 530 540
NLESSNPKGC TPCFCFGHSS VCTNAVGYSV YDISSTFQID EDGWRVEQRD GSEASLEWSS
550 560 570 580 590 600
DRQDIAVISD SYFPRYFIAP VKFLGNQVLS YGQNLSFSFR VDRRDTRLSA EDLVLEGAGL
610 620 630 640 650 660
RVSVPLIAQG NSYPSETTVK YIFRLHEATD YPWRPALSPF EFQKLLNNLT SIKIRGTYSE
670 680 690 700 710 720
RTAGYLDDVT LQSARPGPGV PATWVESCTC PVGYGGQFCE TCLPGYRRET PSLGPYSPCV
730 740 750 760 770 780
LCTCNGHSET CDPETGVCDC RDNTAGPHCE KCSDGYYGDS TLGTSSDCQP CPCPGGSSCA
790 800 810 820 830 840
IVPKTKEVVC THCPTGTAGK RCELCDDGYF GDPLGSNGPV RLCRPCQCND NIDPNAVGNC
850 860 870 880 890 900
NRLTGECLKC IYNTAGFYCD RCKEGFFGNP LAPNPADKCK ACACNPYGTV QQQSSCNPVT
910 920 930 940 950 960
GQCQCLPHVS GRDCGTCDPG YYNLQSGQGC ERCDCHALGS TNGQCDIRTG QCECQPGITG
970 980 990 1000 1010 1020
QHCERCETNH FGFGPEGCKP CDCHHEGSLS LQCKDDGRCE CREGFVGNRC DQCEENYFYN
1030 1040 1050 1060 1070 1080
RSWPGCQECP ACYRLVKDKA AEHRVKLQEL ESLIANLGTG DDMVTDQAFE DRLKEAEREV
1090 1100 1110 1120 1130 1140
TDLLREAQEV KDVDQNLMDR LQRVNSSLHS QISRLQNIRN TIEETGILAE RARSRVESTE
1150 1160 1170 1180 1190 1200
QLIEIASREL EKAKMAAANV SITQPESTGE PNNMTLLAEE ARRLAERHKQ EADDIVRVAK
1210 1220 1230 1240 1250 1260
TANETSAEAY NLLLRTLAGE NQTALEIEEL NRKYEQAKNI SQDLEKQAAR VHEEAKRAGD
1270 1280 1290 1300 1310 1320
KAVEIYASVA QLTPVDSEAL ENEANKIKKE AADLDRLIDQ KLKDYEDLRE DMRGKEHEVK
1330 1340 1350 1360 1370 1380
NLLEKGKAEQ QTADQLLARA DAAKALAEEA AKKGRSTLQE ANDILNNLKD FDRRVNDNKT
1390 1400 1410 1420 1430 1440
AAEEALRRIP AINRTIAEAN EKTREAQLAL GNAAADATEA KNKAHEAERI ASAVQKNATS
1450 1460 1470 1480 1490 1500
TKADAERTFG EVTDLDNEVN GMLRQLEEAE NELKRKQDDA DQDMMMAGMA SQAAQEAELN
1510 1520 1530 1540 1550 1560
ARKAKNSVSS LLSQLNNLLD QLGQLDTVDL NKLNEIEGSL NKAKDEMKAS DLDRKVSDLE
1570 1580 1590 1600
SEARKQEAAI MDYNRDIAEI IKDIHNLEDI KKTLPTGCFN TPSIEKP
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
7 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P02468-34-unmodified | AMDECA... | 34 | N-TAILS | Overall CM. | Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... | 20305284 | |||
| P02468-34-unknown | AMDECA... | 34 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P02468-34-unknown | AMDECA... | 34 | N-TAILS | Overall CM. | auf dem Keller U.: A statistics-based platform for quantitative N-terminome... | 20305283 | |||
| P02468-662-unmodified | TAGYLD... | 662 | N-TAILS | Overall CM. | Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... | 20208520 | |||
| P02468-1224-unknown | ALEIEE... | 1224 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32173 | |||
| P02468-1362-unknown | NDILNN... | 1362 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32174 | |||
| P02468-1363-unknown | DILNNL... | 1363 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32175 | |||
| P02468-1489-unknown | MASQAA... | 1489 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33202 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...GENQTA | 1223 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32173 | |||
| ...TLQEAN | 1361 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32174 | |||
| ...LQEAND | 1362 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC32175 | |||
| ...MMMAGM | 1488 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC33202 | |||
| ...SIEKP | 1607 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ELNE_MOUSE | 1223 | NQTA.|.ALEI | inferred from experiment | unknown | MEROPS | Merops ELNE_MOUSE -> LAMC1_MOUSE @1223 | ||
| ELNE_MOUSE | 1361 | QEAN.|.NDIL | inferred from experiment | unknown | MEROPS | Merops ELNE_MOUSE -> LAMC1_MOUSE @1361 | ||
| ELNE_MOUSE | 1362 | EAND.|.DILN | inferred from experiment | unknown | MEROPS | Merops ELNE_MOUSE -> LAMC1_MOUSE @1362 | ||
| MMP2_MOUSE | 1488 | MAGM.|.MASQ | inferred from experiment | unknown | MEROPS | Merops MMP2_MOUSE -> LAMC1_MOUSE @1488 |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|