P05064: Fructose-bisphosphate aldolase A

General Information

Protein names	- Fructose-bisphosphate aldolase A - 4.1.2.13 - Aldolase 1 - Muscle-type aldolase
Gene names	Aldoa
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P05064

23 N-termini

23 C-termini

26 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPHPYPALTP EQKKELSDIA HRIVAPGKGI LAADESTGSI AKRLQSIGTE NTEENRRFYR
        70         80         90        100        110        120
QLLLTADDRV NPCIGGVILF HETLYQKADD GRPFPQVIKS KGGVVGIKVD KGVVPLAGTN
       130        140        150        160        170        180
GETTTQGLDG LSERCAQYKK DGADFAKWRC VLKIGEHTPS ALAIMENANV LARYASICQQ
       190        200        210        220        230        240
NGIVPIVEPE ILPDGDHDLK RCQYVTEKVL AAVYKALSDH HVYLEGTLLK PNMVTPGHAC
       250        260        270        280        290        300
TQKFSNEEIA MATVTALRRT VPPAVTGVTF LSGGQSEEEA SINLNAINKC PLLKPWALTF
       310        320        330        340        350        360
SYGRALQASA LKAWGGKKEN LKAAQEEYIK RALANSLACQ GKYTPSGQSG AAASESLFIS

NHAY

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

23 N-termini - 23 C-termini - 26 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P05064-2-unknown	PHPYPA...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P05064-31-unknown	LAADES...	31	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33226
P05064-32-unknown	AADEST...	32	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28700
P05064-32-unknown	AADEST...	32	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29613
P05064-34-unknown	DESTGS...	34	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28701
P05064-34-unknown	DESTGS...	34	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29614
P05064-35-unknown	ESTGSI...	35	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29615
P05064-44-unknown	LQSIGT...	44	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33227
P05064-46-unknown	SIGTEN...	46	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33228
P05064-47-unknown	IGTENT...	47	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33229
P05064-47-unknown	IGTENT...	47	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P05064-47-unknown	IGTENT...	47	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P05064-62-unknown	LLLTAD...	62	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33230
P05064-116-unknown	LAGTNG...	116	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33231
P05064-119-unknown	TNGETT...	119	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33232
P05064-135-5oxothiomorpholine-3-carboxylic-acid	CAQYKK...	135		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P05064-150-5oxothiomorpholine-3-carboxylic-acid	CVLKIG...	150		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P05064-153-unknown	KIGEHT...	153	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29616
P05064-163-unknown	AIMENA...	163	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29617
P05064-175-unknown	ASICQQ...	175	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28702
P05064-175-unknown	ASICQQ...	175	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29618
P05064-177-unknown	ICQQNG...	177	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29619
P05064-186-unknown	IVEPEI...	186	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28703
P05064-186-unknown	IVEPEI...	186	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33233
P05064-249-unknown	IAMATV...	249	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29620
P05064-251-unknown	MATVTA...	251	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28704
P05064-251-unknown	MATVTA...	251	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29621
P05064-252-unknown	ATVTAL...	252	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29622
P05064-321-unknown	LKAAQE...	321	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33234
P05064-322-unknown	KAAQEE...	322	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29623
P05064-322-unknown	KAAQEE...	322	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33235

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PGKGIL	30	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33226
...GKGILA	31	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28700
...GKGILA	31	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29613
...GILAAD	33	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28701
...GILAAD	33	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29614
...ILAADE	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29615
...SIAKRL	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33227
...AKRLQS	45	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33228
...KRLQSI	46	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33229
...RFYRQL	61	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33230
...KGVVPL	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33231
...VPLAGT	118	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33232
...CAQYKK	139	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000114587
...WRCVLK	152	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29616
...TPSALA	162	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29617
...VLARYA	174	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28702
...VLARYA	174	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29618
...ARYASI	176	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29619
...NGIVPI	185	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28703
...NGIVPI	185	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33233
...NMVTPG	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118417
...FSNEEI	248	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29620
...NEEIAM	250	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28704
...NEEIAM	250	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29621
...EEIAMA	251	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29622
...GKKENL	320	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33234
...KKENLK	321	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29623
...KKENLK	321	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33235
...SNHAY	364	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	30	KGIL.\|.LAAD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATD_MOUSE	31	GILA.\|.AADE	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ALDOA_MOUSE @31
CATE_MOUSE	31	GILA.\|.AADE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @31
CATD_MOUSE	33	LAAD.\|.DEST	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ALDOA_MOUSE @33
CATE_MOUSE	33	LAAD.\|.DEST	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @33
CATE_MOUSE	34	AADE.\|.ESTG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @34
MMP2_MOUSE	43	AKRL.\|.LQSI	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	45	RLQS.\|.SIGT	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	46	LQSI.\|.IGTE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	61	YRQL.\|.LLLT	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	115	VVPL.\|.LAGT	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	118	LAGT.\|.TNGE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	152	CVLK.\|.KIGE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @152
CATE_MOUSE	162	SALA.\|.AIME	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @162
CATD_MOUSE	174	ARYA.\|.ASIC	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	174	ARYA.\|.ASIC	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @174
CATE_MOUSE	176	YASI.\|.ICQQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @176
CATD_MOUSE	185	IVPI.\|.IVEP	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ALDOA_MOUSE @185
MMP2_MOUSE	185	IVPI.\|.IVEP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	248	NEEI.\|.IAMA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @248
CATD_MOUSE	250	EIAM.\|.MATV	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	250	EIAM.\|.MATV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @250
CATE_MOUSE	251	IAMA.\|.ATVT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @251
MMP2_MOUSE	320	KENL.\|.LKAA	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	321	ENLK.\|.KAAQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ALDOA_MOUSE @321
MMP2_MOUSE	321	ENLK.\|.KAAQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)