TopFIND 4.0

P07919: Cytochrome b-c1 complex subunit 6, mitochondrial

General Information

Protein names	- Cytochrome b-c1 complex subunit 6, mitochondrial - Complex III subunit 6 - Complex III subunit VIII - Cytochrome c1 non-heme 11 kDa protein - Mitochondrial hinge protein - Ubiquinol-cytochrome c reductase complex 11 kDa protein
Gene names	UQCRH
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P07919

3

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MGLEDEQKML TESGDPEEEE EEEEELVDPL TTVREQCEQL EKCVKARERL ELCDERVSSR
70 80 90
SHTEEDCTEE LFDFLHARDH CVAHKLFNNL K

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P07919-2-	GLEDEQ...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07919-2-	GLEDEQ...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P07919-14-unknown	GDPEEE...	14		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P07919-14-unknown	GDPEEE...	14		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC26466
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	RMPI_untreated	23264352
P07919-14-	GDPEEE...	14			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...MLTESG	13	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC26466
	...FNNLK	91	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MPPB_HUMAN	13	TESG.\|.GDPE	inferred from experiment	unknown	MEROPS		Merops MPPB_HUMAN -> QCR6_HUMAN @13

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)