TopFIND 4.0

P13798: Acylamino-acid-releasing enzyme

General Information

Protein names
- Acylamino-acid-releasing enzyme
- AARE
- 3.4.19.1
- Acyl-peptide hydrolase
- APH
- Acylaminoacyl-peptidase
- Oxidized protein hydrolase
- OPH
Gene names APEH
Organism Homo sapiens
Protease Family S09.004
Protease ID S09.004
Chromosome location
UniProt ID P13798

12

N-termini

3

C-termini

0

Cleavages

31

Substrates

Sequence

        10         20         30         40         50         60 
MERQVLLSEP EEAAALYRGL SRQPALSAAC LGPEVTTQYG GQYRTVHTEW TQRDLERMEN 
        70         80         90        100        110        120 
IRFCRQYLVF HDGDSVVFAG PAGNSVETRG ELLSRESPSG TMKAVLRKAG GTGPGEEKQF 
       130        140        150        160        170        180 
LEVWEKNRKL KSFNLSALEK HGPVYEDDCF GCLSWSHSET HLLYVAEKKR PKAESFFQTK 
       190        200        210        220        230        240 
ALDVSASDDE IARLKKPDQA IKGDQFVFYE DWGENMVSKS IPVLCVLDVE SGNISVLEGV 
       250        260        270        280        290        300 
PENVSPGQAF WAPGDAGVVF VGWWHEPFRL GIRFCTNRRS ALYYVDLIGG KCELLSDDSL 
       310        320        330        340        350        360 
AVSSPRLSPD QCRIVYLQYP SLIPHHQCSQ LCLYDWYTKV TSVVVDVVPR QLGENFSGIY 
       370        380        390        400        410        420 
CSLLPLGCWS ADSQRVVFDS AQRSRQDLFA VDTQVGTVTS LTAGGSGGSW KLLTIDQDLM 
       430        440        450        460        470        480 
VAQFSTPSLP PTLKVGFLPS AGKEQSVLWV SLEEAEPIPD IHWGIRVLQP PPEQENVQYA 
       490        500        510        520        530        540 
GLDFEAILLQ PGSPPDKTQV PMVVMPHGGP HSSFVTAWML FPAMLCKMGF AVLLVNYRGS 
       550        560        570        580        590        600 
TGFGQDSILS LPGNVGHQDV KDVQFAVEQV LQEEHFDASH VALMGGSHGG FISCHLIGQY 
       610        620        630        640        650        660 
PETYRACVAR NPVINIASML GSTDIPDWCV VEAGFPFSSD CLPDLSVWAE MLDKSPIRYI 
       670        680        690        700        710        720 
PQVKTPLLLM LGQEDRRVPF KQGMEYYRAL KTRNVPVRLL LYPKSTHALS EVEVESDSFM 
       730    
NAVLWLRTHL GS

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

12 N-termini - 3 C-termini - 0 Cleavages - 31 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates