P14209: CD99 antigen

General Information

Protein names	- CD99 antigen - 12E7 - E2 antigen - Protein MIC2 - T-cell surface glycoprotein E2 - CD99
Gene names	CD99
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P14209

9 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform II of CD99 antigen - Isoform 3 of CD99 antigen

Sequence View

        10         20         30         40         50         60
MARGAALALL LFGLLGVLVA APDGGFDLSD ALPDNENKKP TAIPKKPSAG DDFDLGDAVV
        70         80         90        100        110        120
DGENDDPRPP NPPKPMPNPN PNHPSSSGSF SDADLADGVS GGEGKGGSDG GGSHRKEGEE
       130        140        150        160        170        180
ADAPGVIPGI VGAVVVAVAG AISSFIAYQK KKLCFKENAE QGEVDMESHR NANAEPAVQR

TLLEK         10         20         30         40         50         60
MARGAALALL LFGLLGVLVA APDGGFDLSD ALPDNENKKP TAIPKKPSAG DDFDLGDAVV
        70         80         90        100        110        120
DGENDDPRPP NPPKPMPNPN PNHPSSSGSF SDADLADGVS GGEGKGGSDG GGSHRKEGEE
       130        140        150        160        170        180
ADAPGVIPGI VGAVVVAVAG AISSFIAYQK KKLCFKENAE QGEVDMESHR NANAEPAVQR

TLLEK

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

9 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P14209-1-unknown	MARGAA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt70021
P14209-1-unknown	MARGAA...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt70022
P14209-23-unknown	DGGFDL...	23	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P14209-23-unknown	DGGFDL...	23	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt113286
P14209-87-unknown	SGSFSD...	87	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170434
P14209-87-unknown	SGSFSD...	87	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt170435
P14209-87-	SGSFSD...	87		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P14209-89-	SFSDAD...	89		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P14209-89-	SFSDAD...	89		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P14209-89-	SFSDAD...	89		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P14209-89-	SFSDAD...	89		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P14209-89-	SFSDAD...	89		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P14209-89-	SFSDAD...	89		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P14209-89-	SFSDAD...	89		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P14209-89-unknown	SFSDAD...	89		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P14209-89-unknown	SFSDAD...	89	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161363
P14209-89-unknown	SFSDAD...	89	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161364
P14209-90-	FSDADL...	90		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P14209-90-unknown	FSDADL...	90	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172139
P14209-90-unknown	FSDADL...	90	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt172140
P14209-97-unknown	DGVSGG...	97	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18729
P14209-97-unknown	DGVSGG...	97	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt141338
P14209-97-unknown	DGVSGG...	97	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142239

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DADLAD	96	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18729
...DADLAD	96	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt124505
...DADLAD	96	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125427
...TLLEK	185	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TLLEK	185	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt65640

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1B_HUMAN	96	DLAD.\|.DGVS	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)