P19404: NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

General Information

Protein names	- NADH dehydrogenase ubiquinone] flavoprotein 2, mitochondrial - 1.6.99.3 - 7.1.1.2 - NADH-ubiquinone oxidoreductase 24 kDa subunit
Gene names	NDUFV2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P19404

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MFFSAALRAR AAGLTAHWGR HVRNLHKTVM QNGAGGALFV HRDTPENNPD TPFDFTPENY
        70         80         90        100        110        120
KRIEAIVKNY PEGHKAAAVL PVLDLAQRQN GWLPISAMNK VAEVLQVPPM RVYEVATFYT
       130        140        150        160        170        180
MYNRKPVGKY HIQVCTTTPC MLRNSDSILE AIQKKLGIKV GETTPDKLFT LIEVECLGAC
       190        200        210        220        230        240
VNAPMVQIND NYYEDLTAKD IEEIIDELKA GKIPKPGPRS GRFSCEPAGG LTSLTEPPKG

PGFGVQAGL

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P19404-25-unknown	LHKTVM...	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC26471
P19404-32-unknown	NGAGGA...	32	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P19404-33-unknown	GAGGAL...	33	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P19404-33-unknown	GAGGAL...	33		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19404-33-unknown	GAGGAL...	33		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
P19404-33-	GAGGAL...	33		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...RHVRNL	24	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC26471
	...VQAGL	249	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MPPB_HUMAN	24	VRNL.\|.LHKT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Caspase-specific and nonspecifi... (M16.003)	16179924,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)