P21281: V-type proton ATPase subunit B, brain isoform

General Information

Protein names	- V-type proton ATPase subunit B, brain isoform - V-ATPase subunit B 2 - Endomembrane proton pump 58 kDa subunit - HO57 - Vacuolar proton pump subunit B 2
Gene names	ATP6V1B2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P21281

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MALRAMRGIV NGAAPELPVP TGGPAVGARE QALAVSRNYL SQPRLTYKTV SGVNGPLVIL
        70         80         90        100        110        120
DHVKFPRYAE IVHLTLPDGT KRSGQVLEVS GSKAVVQVFE GTSGIDAKKT SCEFTGDILR
       130        140        150        160        170        180
TPVSEDMLGR VFNGSGKPID RGPVVLAEDF LDIMGQPINP QCRIYPEEMI QTGISAIDGM
       190        200        210        220        230        240
NSIARGQKIP IFSAAGLPHN EIAAQICRQA GLVKKSKDVV DYSEENFAIV FAAMGVNMET
       250        260        270        280        290        300
ARFFKSDFEE NGSMDNVCLF LNLANDPTIE RIITPRLALT TAEFLAYQCE KHVLVILTDM
       310        320        330        340        350        360
SSYAEALREV SAAREEVPGR RGFPGYMYTD LATIYERAGR VEGRNGSITQ IPILTMPNDD
       370        380        390        400        410        420
ITHPIPDLTG YITEGQIYVD RQLHNRQIYP PINVLPSLSR LMKSAIGEGM TRKDHADVSN
       430        440        450        460        470        480
QLYACYAIGK DVQAMKAVVG EEALTSDDLL YLEFLQKFER NFIAQGPYEN RTVFETLDIG
       490        500        510
WQLLRIFPKE MLKRIPQSTL SEFYPRDSAK H

Isoforms

Sequence View

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Evidence Codes:

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P21281-1-unknown	MALRAM...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P21281-8-	GIVNGA...	8		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P21281-12-	GAAPEL...	12		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P21281-12-	GAAPEL...	12		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P21281-13-	AAPELP...	13		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P21281-13-	AAPELP...	13		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
P21281-13-	AAPELP...	13		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P21281-13-	AAPELP...	13		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P21281-13-	AAPELP...	13		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P21281-13-	AAPELP...	13		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P21281-13-	AAPELP...	13		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P21281-13-	AAPELP...	13		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P21281-13-unknown	AAPELP...	13		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P21281-217-	KDVVDY...	217		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...DSAKH	511	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)