P26041: Moesin {ECO:0000303|PubMed:1429901}

General Information

Protein names	- Moesin {ECO:0000303\|PubMed:1429901} - Membrane-organizing extension spike protein
Gene names	Msn
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P26041

20 N-termini

16 C-termini

15 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPKTISVRVT TMDAELEFAI QPNTTGKQLF DQVVKTIGLR EVWFFGLQYQ DTKAFSTWLK
        70         80         90        100        110        120
LNKKVTAQDV RKESPLLFKF RAKFYPEDVS EELIQDITQR LFFLQVKEGI LNDDIYCPPE
       130        140        150        160        170        180
TAVLLASYAV QSKYGDFNKE VHKSGYLAGD KLLPQRVLEQ HKLNKDQWEE RIQVWHEEHR
       190        200        210        220        230        240
GMLREDAVLE YLKIAQDLEM YGVNYFSIKN KKGSELWLGV DALGLNIYEQ NDRLTPKIGF
       250        260        270        280        290        300
PWSEIRNISF NDKKFVIKPI DKKAPDFVFY APRLRINKRI LALCMGNHEL YMRRRKPDTI
       310        320        330        340        350        360
EVQQMKAQAR EEKHQKQMER ALLENEKKKR ELAEKEKEKI EREKEELMEK LKQIEEQTKK
       370        380        390        400        410        420
AQQELEEQTR RALELEQERK RAQSEAEKLA KERQEAEEAK EALLQASRDQ KKTQEQLASE
       430        440        450        460        470        480
MAELTARISQ LEMARKKKES EAVEWQQKAQ MVQEDLEKTR AELKTAMSTP HVAEPAENEH
       490        500        510        520        530        540
DEQDENGAEA SAELRADAMA KDRSEEERTT EAEKNERVQK HLKALTSELA NARDESKKTA
       550        560        570
NDMIHAENMR LGRDKYKTLR QIRQGNTKQR IDEFESM

Isoforms

Sequence View

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

20 N-termini - 16 C-termini - 15 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P26041-2-unknown	PKTISV...	2		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P26041-2-unknown	PKTISV...	2		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P26041-59-unknown	LKLNKK...	59		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28844
P26041-82-unknown	AKFYPE...	82		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33477
P26041-144-unknown	SGYLAG...	144		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33478
P26041-226-unknown	NIYEQN...	226		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29876
P26041-262-unknown	KKAPDF...	262		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33479
P26041-263-unknown	KAPDFV...	263		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33480
P26041-264-unknown	APDFVF...	264		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33481
P26041-285-unmodified	MGNHEL...	285			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P26041-302-unknown	VQQMKA...	302		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29877
P26041-323-unknown	LENEKK...	323		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29878
P26041-394-Pyrrolidone carboxylic acid	QEAEEA...	394	pyrrolidone carboxylic acid-		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P26041-394-Pyrrolidone carboxylic acid	QEAEEA...	394	pyrrolidone carboxylic acid-		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P26041-394-acetylation	QEAEEA...	394	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P26041-418-unknown	ASEMAE...	418		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29879
P26041-445-unknown	WQQKAQ...	445		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33482
P26041-449-unmodified	AQMVQE...	449			N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P26041-449-unmodified	AQMVQE...	449			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P26041-451-unknown	MVQEDL...	451		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33483
P26041-452-unknown	VQEDLE...	452		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33484
P26041-525-unknown	LTSELA...	525		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33485
P26041-526-unknown	TSELAN...	526		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29880

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AFSTWL	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28844
...LFKFRA	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33477
...KEVHKS	143	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33478
...DALGLN	225	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29876
...IKPIDK	261	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33479
...KPIDKK	262	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33480
...PIDKKA	263	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33481
...PDTIEV	301	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29877
...MERALL	322	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29878
...TQEQLA	417	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29879
...SEAVEW	444	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33482
...QQKAQM	450	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33483
...QKAQMV	451	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33484
...KHLKAL	524	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33485
...HLKALT	525	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29880
...EFESM	577	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	58	STWL.\|.LKLN	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> MOES_MOUSE @58
MMP2_MOUSE	81	KFRA.\|.AKFY	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	143	VHKS.\|.SGYL	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	225	LGLN.\|.NIYE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MOES_MOUSE @225
MMP2_MOUSE	261	PIDK.\|.KKAP	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	262	IDKK.\|.KAPD	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	263	DKKA.\|.APDF	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	301	TIEV.\|.VQQM	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MOES_MOUSE @301
CATE_MOUSE	322	RALL.\|.LENE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MOES_MOUSE @322
CATE_MOUSE	417	EQLA.\|.ASEM	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MOES_MOUSE @417
MMP2_MOUSE	444	AVEW.\|.WQQK	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	450	KAQM.\|.MVQE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	451	AQMV.\|.VQED	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	524	LKAL.\|.LTSE	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
CATE_MOUSE	525	KALT.\|.TSEL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> MOES_MOUSE @525

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)