TopFIND 4.0

P26883: Peptidyl-prolyl cis-trans isomerase FKBP1A

General Information

Protein names	- Peptidyl-prolyl cis-trans isomerase FKBP1A - PPIase FKBP1A - 5.2.1.8 {ECO:0000250\|UniProtKB:P62942} - 12 kDa FK506-binding protein - 12 kDa FKBP - FKBP-12 - Calstabin-1 - FK506-binding protein 1A - FKBP-1A - Immunophilin FKBP12 - Rotamase
Gene names	Fkbp1a
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P26883

10

N-termini

6

C-termini

5

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFT LGKQEVIRGW
70 80 90 100
EEGVAQMSVG QRAKLIISSD YAYGATGHPG IIPPHATLVF DVELLKLE

Isoforms

Sequence View

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Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

10 N-termini - 6 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P26883-2-unknown	MGVQVE...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P26883-2-unknown	MGVQVE...	1			N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P26883-2-unmodified	GVQVET...	2			N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P26883-2-unmodified	GVQVET...	2			unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520
P26883-2-unmodified	GVQVET...	2			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P26883-2-Acetylation	GVQVET...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P26883-2-Acetylation	GVQVET...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P26883-12-unknown	DGRTFP...	12		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P26883-24-unmodified	VVHYTG...	24			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P26883-27-unknown	YTGMLE...	27		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33491
P26883-49-unknown	FTLGKQ...	49		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33492
P26883-63-unknown	GVAQMS...	63		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29886
P26883-76-unknown	IISSDY...	76		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33493
P26883-99-unknown	VFDVEL...	99		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33494

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...TCVVHY	26	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33491
	...NKPFKF	48	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33492
	...RGWEEG	62	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29886
	...QRAKLI	75	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33493
	...PHATLV	98	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33494
	...LLKLE	108	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	26	VVHY.\|.YTGM	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	48	PFKF.\|.FTLG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	62	WEEG.\|.GVAQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> FKB1A_MOUSE @62
MMP2_MOUSE	75	AKLI.\|.IISS	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> FKB1A_MOUSE @75
MMP2_MOUSE	98	ATLV.\|.VFDV	inferred from experiment	unknown	MEROPS		Merops MMP2_MOUSE -> FKB1A_MOUSE @98

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)