P28070: Proteasome subunit beta type-4
Protein names | - Proteasome subunit beta type-4 - 3.4.25.1 {ECO:0000269|PubMed:27176742} - 26 kDa prosomal protein - HsBPROS26 - PROS-26 - Macropain beta chain - Multicatalytic endopeptidase complex beta chain - Proteasome beta chain - Proteasome chain 3 - HsN3 |
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Gene names | PSMB4 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | T01.987 |
Chromosome location | |
UniProt ID | P28070 |
7
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEAFLGSRSG LWAGGPAPGQ FYRIPSTPDS FMDPASALYR GPITRTQNPM VTGTSVLGVK
70 80 90 100 110 120
FEGGVVIAAD MLGSYGSLAR FRNISRIMRV NNSTMLGASG DYADFQYLKQ VLGQMVIDEE
130 140 150 160 170 180
LLGDGHSYSP RAIHSWLTRA MYSRRSKMNP LWNTMVIGGY ADGESFLGYV DMLGVAYEAP
190 200 210 220 230 240
SLATGYGAYL AQPLLREVLE KQPVLSQTEA RDLVERCMRV LYYRDARSYN RFQIATVTEK
250 260
GVEIEGPLST ETNWDIAHMI SGFE
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
7 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P28070-1-acetylation | MEAFLG... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
P28070-1-acetylation | MEAFLG... | 1 | acetylation- | other | CNRS/ISV | Large_scale_NTA_Human | |||
P28070-1-acetylation | MEAFLG... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
P28070-30- | SFMDPA... | 30 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P28070-30- | SFMDPA... | 30 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P28070-30- | SFMDPA... | 30 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P28070-30- | SFMDPA... | 30 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
P28070-31- | FMDPAS... | 31 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P28070-46- | TQNPMV... | 46 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
P28070-46- | TQNPMV... | 46 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
P28070-46- | TQNPMV... | 46 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
P28070-46- | TQNPMV... | 46 | Subtiligase Based Positive Selection | Wells | MM1SDBJurkat_Untreated | 23264352 | |||
P28070-46- | TQNPMV... | 46 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
P28070-46- | TQNPMV... | 46 | N-TAILS | Overall Laboratory | Lange_Huesgen_et_al-RBC | ||||
P28070-46-unknown | TQNPMV... | 46 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P28070-197-Pyrrolidone carboxylic acid (Glu) | EVLEKQ... | 197 | pyrrolidone carboxylic acid- | N-TAILS | Overall Laboratory | Lange_Huesgen_et_al-RBC | |||
P28070-197-acetylation | EVLEKQ... | 197 | acetylation- | N-TAILS | Overall Laboratory | Lange_Huesgen_et_al-RBC |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...ISGFE | 264 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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