P33240: Cleavage stimulation factor subunit 2

General Information

Protein names	- Cleavage stimulation factor subunit 2 - CF-1 64 kDa subunit - Cleavage stimulation factor 64 kDa subunit - CSTF 64 kDa subunit - CstF-64
Gene names	CSTF2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P33240

10 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAGLTVRDPA VDRSLRSVFV GNIPYEATEE QLKDIFSEVG PVVSFRLVYD RETGKPKGYG
        70         80         90        100        110        120
FCEYQDQETA LSAMRNLNGR EFSGRALRVD NAASEKNKEE LKSLGTGAPV IESPYGETIS
       130        140        150        160        170        180
PEDAPESISK AVASLPPEQM FELMKQMKLC VQNSPQEARN MLLQNPQLAY ALLQAQVVMR
       190        200        210        220        230        240
IVDPEIALKI LHRQTNIPTL IAGNPQPVHG AGPGSGSNVS MNQQNPQAPQ AQSLGGMHVN
       250        260        270        280        290        300
GAPPLMQASM QGGVPAPGQM PAAVTGPGPG SLAPGGGMQA QVGMPGSGPV SMERGQVPMQ
       310        320        330        340        350        360
DPRAAMQRGS LPANVPTPRG LLGDAPNDPR GGTLLSVTGE VEPRGYLGPP HQGPPMHHVP
       370        380        390        400        410        420
GHESRGPPPH ELRGGPLPEP RPLMAEPRGP MLDQRGPPLD GRGGRDPRGI DARGMEARAM
       430        440        450        460        470        480
EARGLDARGL EARAMEARAM EARAMEARAM EARAMEVRGM EARGMDTRGP VPGPRGPIPS
       490        500        510        520        530        540
GMQGPSPINM GAVVPQGSRQ VPVMQGTGMQ GASIQGGSQP GGFSPGQNQV TPQDHEKAAL
       550        560        570
IMQVLQLTAD QIAMLPPEQR QSILILKEQI QKSTGAP

Isoforms

- Isoform 2 of Cleavage stimulation factor subunit 2

Sequence View

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Protein Neighborhood

Domains & Features

10 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P33240-1-unknown	MAGLTV...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P33240-1-unknown	MAGLTV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71943
P33240-103-	SLGTGA...	103		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P33240-103-	SLGTGA...	103		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P33240-103-unknown	SLGTGA...	103	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176168
P33240-310-	SLPANV...	310		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P33240-310-unknown	SLPANV...	310	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173878
P33240-336-unknown	SVTGEV...	336	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt176859
P33240-336-	SVTGEV...	336		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P33240-348-unknown	GPPHQG...	348	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC5805
P33240-348-unknown	GPPHQG...	348	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt150554
P33240-492-	AVVPQG...	492		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P33240-492-unknown	AVVPQG...	492	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt173880

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PRGYLG	347	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC5805
...PRGYLG	347	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133951
...STGAP	577	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...STGAP	577	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67561

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATL1_HUMAN	347	GYLG.\|.GPPH	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)